Chen WY - Search Results

1

Role for Dpy-30 in ES cell-fate specification by regulation of H3K4 methylation within bivalent domains.

Jiang H, Shukla A, Wang X, Chen WY, Bernstein BE, Roeder RG. Jiang H, et al. Among authors: chen wy. Cell. 2011 Feb 18;144(4):513-25. doi: 10.1016/j.cell.2011.01.020. Cell. 2011. PMID: 21335234 Free PMC article.

2

Integrative epigenomic analysis identifies biomarkers and therapeutic targets in adult B-acute lymphoblastic leukemia.

Geng H, Brennan S, Milne TA, Chen WY, Li Y, Hurtz C, Kweon SM, Zickl L, Shojaee S, Neuberg D, Huang C, Biswas D, Xin Y, Racevskis J, Ketterling RP, Luger SM, Lazarus H, Tallman MS, Rowe JM, Litzow MR, Guzman ML, Allis CD, Roeder RG, Müschen M, Paietta E, Elemento O, Melnick AM. Geng H, et al. Among authors: chen wy. Cancer Discov. 2012 Nov;2(11):1004-23. doi: 10.1158/2159-8290.CD-12-0208. Epub 2012 Oct 29. Cancer Discov. 2012. PMID: 23107779 Free PMC article.

3

An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting.

Cai L, Rothbart SB, Lu R, Xu B, Chen WY, Tripathy A, Rockowitz S, Zheng D, Patel DJ, Allis CD, Strahl BD, Song J, Wang GG. Cai L, et al. Among authors: chen wy. Mol Cell. 2013 Feb 7;49(3):571-82. doi: 10.1016/j.molcel.2012.11.026. Epub 2012 Dec 27. Mol Cell. 2013. PMID: 23273982 Free PMC article.

4

A stable transcription factor complex nucleated by oligomeric AML1-ETO controls leukaemogenesis.

Sun XJ, Wang Z, Wang L, Jiang Y, Kost N, Soong TD, Chen WY, Tang Z, Nakadai T, Elemento O, Fischle W, Melnick A, Patel DJ, Nimer SD, Roeder RG. Sun XJ, et al. Among authors: chen wy. Nature. 2013 Aug 1;500(7460):93-7. doi: 10.1038/nature12287. Epub 2013 Jun 30. Nature. 2013. PMID: 23812588 Free PMC article.

5

SET1 and p300 act synergistically, through coupled histone modifications, in transcriptional activation by p53.

Tang Z, Chen WY, Shimada M, Nguyen UT, Kim J, Sun XJ, Sengoku T, McGinty RK, Fernandez JP, Muir TW, Roeder RG. Tang Z, et al. Among authors: chen wy. Cell. 2013 Jul 18;154(2):297-310. doi: 10.1016/j.cell.2013.06.027. Cell. 2013. PMID: 23870121 Free PMC article.

6

A TAF4 coactivator function for E proteins that involves enhanced TFIID binding.

Chen WY, Zhang J, Geng H, Du Z, Nakadai T, Roeder RG. Chen WY, et al. Genes Dev. 2013 Jul 15;27(14):1596-609. doi: 10.1101/gad.216192.113. Genes Dev. 2013. PMID: 23873942 Free PMC article.

7

Self-enforcing feedback activation between BCL6 and pre-B cell receptor signaling defines a distinct subtype of acute lymphoblastic leukemia.

Geng H, Hurtz C, Lenz KB, Chen Z, Baumjohann D, Thompson S, Goloviznina NA, Chen WY, Huan J, LaTocha D, Ballabio E, Xiao G, Lee JW, Deucher A, Qi Z, Park E, Huang C, Nahar R, Kweon SM, Shojaee S, Chan LN, Yu J, Kornblau SM, Bijl JJ, Ye BH, Ansel KM, Paietta E, Melnick A, Hunger SP, Kurre P, Tyner JW, Loh ML, Roeder RG, Druker BJ, Burger JA, Milne TA, Chang BH, Müschen M. Geng H, et al. Among authors: chen z, chen wy. Cancer Cell. 2015 Mar 9;27(3):409-25. doi: 10.1016/j.ccell.2015.02.003. Cancer Cell. 2015. PMID: 25759025 Free PMC article.

8

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development.

Lu R, Wang P, Parton T, Zhou Y, Chrysovergis K, Rockowitz S, Chen WY, Abdel-Wahab O, Wade PA, Zheng D, Wang GG. Lu R, et al. Among authors: chen wy. Cancer Cell. 2016 Jul 11;30(1):92-107. doi: 10.1016/j.ccell.2016.05.008. Epub 2016 Jun 23. Cancer Cell. 2016. PMID: 27344947 Free PMC article.

9

Architecture of Pol II(G) and molecular mechanism of transcription regulation by Gdown1.

Jishage M, Yu X, Shi Y, Ganesan SJ, Chen WY, Sali A, Chait BT, Asturias FJ, Roeder RG. Jishage M, et al. Among authors: chen wy. Nat Struct Mol Biol. 2018 Sep;25(9):859-867. doi: 10.1038/s41594-018-0118-5. Epub 2018 Sep 6. Nat Struct Mol Biol. 2018. PMID: 30190596 Free PMC article.

10

Gene-Specific H1 Eviction through a Transcriptional Activator→p300→NAP1→H1 Pathway.

Shimada M, Chen WY, Nakadai T, Onikubo T, Guermah M, Rhodes D, Roeder RG. Shimada M, et al. Among authors: chen wy. Mol Cell. 2019 Apr 18;74(2):268-283.e5. doi: 10.1016/j.molcel.2019.02.016. Epub 2019 Mar 19. Mol Cell. 2019. PMID: 30902546 Free PMC article.

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