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Design and optimization of potent and orally bioavailable tetrahydronaphthalene Raf inhibitors.
Gould AE, Adams R, Adhikari S, Aertgeerts K, Afroze R, Blackburn C, Calderwood EF, Chau R, Chouitar J, Duffey MO, England DB, Farrer C, Forsyth N, Garcia K, Gaulin J, Greenspan PD, Guo R, Harrison SJ, Huang SC, Iartchouk N, Janowick D, Kim MS, Kulkarni B, Langston SP, Liu JX, Ma LT, Menon S, Mizutani H, Paske E, Renou CC, Rezaei M, Rowland RS, Sintchak MD, Smith MD, Stroud SG, Tregay M, Tian Y, Veiby OP, Vos TJ, Vyskocil S, Williams J, Xu T, Yang JJ, Yano J, Zeng H, Zhang DM, Zhang Q, Galvin KM. Gould AE, et al. Among authors: adhikari s. J Med Chem. 2011 Mar 24;54(6):1836-46. doi: 10.1021/jm101479y. Epub 2011 Feb 22. J Med Chem. 2011. PMID: 21341678
Optimization of tetrahydronaphthalene inhibitors of Raf with selectivity over hERG.
Huang SC, Adhikari S, Afroze R, Brewer K, Calderwood EF, Chouitar J, England DB, Fisher C, Galvin KM, Gaulin J, Greenspan PD, Harrison SJ, Kim MS, Langston SP, Ma LT, Menon S, Mizutani H, Rezaei M, Smith MD, Zhang DM, Gould AE. Huang SC, et al. Among authors: adhikari s. Bioorg Med Chem Lett. 2016 Feb 15;26(4):1156-60. doi: 10.1016/j.bmcl.2016.01.049. Epub 2016 Jan 21. Bioorg Med Chem Lett. 2016. PMID: 26804230
Discovery and optimization of pyrazolopyrimidine sulfamates as ATG7 inhibitors.
Huang SC, Adhikari S, Brownell JE, Calderwood EF, Chouitar J, D'Amore NR, England DB, Foley K, Harrison SJ, LeRoy PJ, Lok D, Lublinsky A, Ma LT, Menon S, Yang Y, Zhang J, Gould AE. Huang SC, et al. Among authors: adhikari s. Bioorg Med Chem. 2020 Oct 1;28(19):115681. doi: 10.1016/j.bmc.2020.115681. Epub 2020 Aug 4. Bioorg Med Chem. 2020. PMID: 32912429 Free article.
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer.
Soucy TA, Smith PG, Milhollen MA, Berger AJ, Gavin JM, Adhikari S, Brownell JE, Burke KE, Cardin DP, Critchley S, Cullis CA, Doucette A, Garnsey JJ, Gaulin JL, Gershman RE, Lublinsky AR, McDonald A, Mizutani H, Narayanan U, Olhava EJ, Peluso S, Rezaei M, Sintchak MD, Talreja T, Thomas MP, Traore T, Vyskocil S, Weatherhead GS, Yu J, Zhang J, Dick LR, Claiborne CF, Rolfe M, Bolen JB, Langston SP. Soucy TA, et al. Among authors: adhikari s. Nature. 2009 Apr 9;458(7239):732-6. doi: 10.1038/nature07884. Nature. 2009. PMID: 19360080
Bowel Obstruction After Gastric Bypass Surgery: A Narrative Review.
George AP, Erekat KW, Mohammed C, Kaur N, Kaur A, Adhikari S, Rahman A, Lakshmannagari H, Tavera-Castaño CD, Vallakati M, Kaur S, Nazir Z. George AP, et al. Among authors: adhikari s. Cureus. 2024 Dec 9;16(12):e75386. doi: 10.7759/cureus.75386. eCollection 2024 Dec. Cureus. 2024. PMID: 39781153 Free PMC article. Review.
Rehabilitation at Home Using Mobile Health for Older Adults Hospitalized for Ischemic Heart Disease: The RESILIENT Randomized Clinical Trial.
Dodson JA, Adhikari S, Schoenthaler A, Hochman JS, Sweeney G, George B, Marzo K, Jennings LA, Kovell LC, Vorsanger M, Pena S, Meng Y, Varghese A, Johanek C, Rojas M, McConnell R, Whiteson J, Troxel AB. Dodson JA, et al. Among authors: adhikari s. JAMA Netw Open. 2025 Jan 2;8(1):e2453499. doi: 10.1001/jamanetworkopen.2024.53499. JAMA Netw Open. 2025. PMID: 39775808 Free article. Clinical Trial.
The Prevalence of Physical Intimate Partner Violence During Pregnancy and the Postpartum Period: A Systematic Review With Implications for Probable Violence-Caused Brain Injury Among Child Bearers.
Adhikari SP, Stranges TN, Lorenz BR, Marshall RA, Jiang N, van Donkelaar P. Adhikari SP, et al. Trauma Violence Abuse. 2025 Jan 2:15248380241309292. doi: 10.1177/15248380241309292. Online ahead of print. Trauma Violence Abuse. 2025. PMID: 39744846 Free article. Review.
1,566 results