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HIV-1 escape from the CCR5 antagonist maraviroc associated with an altered and less-efficient mechanism of gp120-CCR5 engagement that attenuates macrophage tropism.
Roche M, Jakobsen MR, Sterjovski J, Ellett A, Posta F, Lee B, Jubb B, Westby M, Lewin SR, Ramsland PA, Churchill MJ, Gorry PR. Roche M, et al. Among authors: lewin sr. J Virol. 2011 May;85(9):4330-42. doi: 10.1128/JVI.00106-11. Epub 2011 Feb 23. J Virol. 2011. PMID: 21345957 Free PMC article.
Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome.
Gray L, Sterjovski J, Churchill M, Ellery P, Nasr N, Lewin SR, Crowe SM, Wesselingh SL, Cunningham AL, Gorry PR. Gray L, et al. Among authors: lewin sr. Virology. 2005 Jul 5;337(2):384-98. doi: 10.1016/j.virol.2005.04.034. Virology. 2005. PMID: 15916792 Free article.
Pathogenicity and immunogenicity of attenuated, nef-deleted HIV-1 strains in vivo.
Gorry PR, McPhee DA, Verity E, Dyer WB, Wesselingh SL, Learmont J, Sullivan JS, Roche M, Zaunders JJ, Gabuzda D, Crowe SM, Mills J, Lewin SR, Brew BJ, Cunningham AL, Churchill MJ. Gorry PR, et al. Among authors: lewin sr. Retrovirology. 2007 Sep 23;4:66. doi: 10.1186/1742-4690-4-66. Retrovirology. 2007. PMID: 17888184 Free PMC article.
Impaired quality of the hepatitis B virus (HBV)-specific T-cell response in human immunodeficiency virus type 1-HBV coinfection.
Chang JJ, Sirivichayakul S, Avihingsanon A, Thompson AJ, Revill P, Iser D, Slavin J, Buranapraditkun S, Marks P, Matthews G, Cooper DA, Kent SJ, Cameron PU, Sasadeusz J, Desmond P, Locarnini S, Dore GJ, Ruxrungtham K, Lewin SR. Chang JJ, et al. Among authors: lewin sr. J Virol. 2009 Aug;83(15):7649-58. doi: 10.1128/JVI.00183-09. Epub 2009 May 20. J Virol. 2009. PMID: 19458009 Free PMC article.
No increase in hepatitis B virus (HBV)-specific CD8+ T cells in patients with HIV-1-HBV coinfections following HBV-active highly active antiretroviral therapy.
Crane M, Sirivichayakul S, Chang JJ, Avihingsanon A, Ubolyam S, Buranapraditkun S, Thantiworasit P, Wightman F, Locarnini S, Matthews G, Dore GJ, Ruxrungtham K, Lewin SR. Crane M, et al. Among authors: lewin sr. J Virol. 2010 Mar;84(6):2657-65. doi: 10.1128/JVI.02124-09. Epub 2010 Jan 6. J Virol. 2010. PMID: 20053751 Free PMC article.
409 results