Petrelli R - Search Results

1

Synthesis and biological activity of novel N6-substituted and 2,N6-disubstituted adenine ribo- and 3'-C-methyl-ribonucleosides as antitumor agents.

Cappellacci L, Petrelli R, Franchetti P, Vita P, Kusumanchi P, Kumar M, Jayaram HN, Zhou B, Yen Y, Grifantini M. Cappellacci L, et al. Among authors: petrelli r. Eur J Med Chem. 2011 May;46(5):1499-504. doi: 10.1016/j.ejmech.2011.01.055. Epub 2011 Feb 3. Eur J Med Chem. 2011. PMID: 21349610

2

Stereoselective synthesis of nicotinamide beta-riboside and nucleoside analogs.

Franchetti P, Pasqualini M, Petrelli R, Ricciutelli M, Vita P, Cappellacci L. Franchetti P, et al. Among authors: petrelli r. Bioorg Med Chem Lett. 2004 Sep 20;14(18):4655-8. doi: 10.1016/j.bmcl.2004.06.093. Bioorg Med Chem Lett. 2004. PMID: 15324883

3

Synthesis, conformational analysis, and biological activity of new analogues of thiazole-4-carboxamide adenine dinucleotide (TAD) as IMP dehydrogenase inhibitors.

Franchetti P, Cappellacci L, Pasqualini M, Petrelli R, Jayaprakasan V, Jayaram HN, Boyd DB, Jain MD, Grifantini M. Franchetti P, et al. Among authors: petrelli r. Bioorg Med Chem. 2005 Mar 15;13(6):2045-53. doi: 10.1016/j.bmc.2005.01.007. Bioorg Med Chem. 2005. PMID: 15727858

4

Synthesis, biological evaluation, and molecular modeling of ribose-modified adenosine analogues as adenosine receptor agonists.

Cappellacci L, Franchetti P, Pasqualini M, Petrelli R, Vita P, Lavecchia A, Novellino E, Costa B, Martini C, Klotz KN, Grifantini M. Cappellacci L, et al. Among authors: petrelli r. J Med Chem. 2005 Mar 10;48(5):1550-62. doi: 10.1021/jm049408n. J Med Chem. 2005. PMID: 15743197

5

Antitumor activity of C-methyl-beta-D-ribofuranosyladenine nucleoside ribonucleotide reductase inhibitors.

Franchetti P, Cappellacci L, Pasqualini M, Petrelli R, Vita P, Jayaram HN, Horvath Z, Szekeres T, Grifantini M. Franchetti P, et al. Among authors: petrelli r. J Med Chem. 2005 Jul 28;48(15):4983-9. doi: 10.1021/jm048944c. J Med Chem. 2005. PMID: 16033277

6

Synthesis and biological evaluation of NAD analogs as human pyridine nucleotide adenylyltransferase inhibitors.

Franchetti P, Petrelli R, Cappellacci L, Pasqualini M, Vita P, Sorci L, Mazzola F, Raffaelli N, Magni G. Franchetti P, et al. Among authors: petrelli r. Nucleosides Nucleotides Nucleic Acids. 2005;24(5-7):477-9. doi: 10.1081/ncn-200060013. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16247974

7

Ribose-modified mizoribine analogues: synthesis and biological evaluation.

Franchetti P, Pasqualini M, Cappellacci L, Petrelli R, Vita P, Grifantini M. Franchetti P, et al. Among authors: petrelli r. Nucleosides Nucleotides Nucleic Acids. 2005;24(10-12):2023-7. doi: 10.1080/15257770500334673. Nucleosides Nucleotides Nucleic Acids. 2005. PMID: 16438062

8

Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis.

Sorci L, Cimadamore F, Scotti S, Petrelli R, Cappellacci L, Franchetti P, Orsomando G, Magni G. Sorci L, et al. Among authors: petrelli r. Biochemistry. 2007 Apr 24;46(16):4912-22. doi: 10.1021/bi6023379. Epub 2007 Apr 3. Biochemistry. 2007. PMID: 17402747

9

5'-Carbamoyl derivatives of 2'-C-methyl-purine nucleosides as selective A1 adenosine receptor agonists: affinity, efficacy, and selectivity for A1 receptor from different species.

Cappellacci L, Franchetti P, Vita P, Petrelli R, Lavecchia A, Costa B, Spinetti F, Martini C, Klotz KN, Grifantini M. Cappellacci L, et al. Among authors: petrelli r. Bioorg Med Chem. 2008 Jan 1;16(1):336-53. doi: 10.1016/j.bmc.2007.09.035. Epub 2007 Sep 22. Bioorg Med Chem. 2008. PMID: 17933541

10

Inhibition of HIV-1 replication in macrophages by red blood cell-mediated delivery of a heterodinucleotide of lamivudine and tenofovir.

Franchetti P, Cappellacci L, Petrelli R, Vita P, Grifantini M, Rossi L, Pierigé F, Serafini S, Magnani M, Balestra E, Perno CF. Franchetti P, et al. Among authors: petrelli r. Nucleosides Nucleotides Nucleic Acids. 2007;26(8-9):953-7. doi: 10.1080/15257770701508067. Nucleosides Nucleotides Nucleic Acids. 2007. PMID: 18058516

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