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Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs.
Manoharan M, Akinc A, Pandey RK, Qin J, Hadwiger P, John M, Mills K, Charisse K, Maier MA, Nechev L, Greene EM, Pallan PS, Rozners E, Rajeev KG, Egli M. Manoharan M, et al. Among authors: egli m. Angew Chem Int Ed Engl. 2011 Mar 1;50(10):2284-8. doi: 10.1002/anie.201006519. Epub 2011 Jan 31. Angew Chem Int Ed Engl. 2011. PMID: 21351337 Free PMC article. No abstract available.
Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications.
Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Egli M, et al. Biochemistry. 2005 Jun 28;44(25):9045-57. doi: 10.1021/bi050574m. Biochemistry. 2005. PMID: 15966728 Free article.
432 results