Treadway JL - Search Results

1

Impact of a glycogen phosphorylase inhibitor and metformin on basal and glucagon-stimulated hepatic glucose flux in conscious dogs.

Torres TP, Sasaki N, Donahue EP, Lacy B, Printz RL, Cherrington AD, Treadway JL, Shiota M. Torres TP, et al. Among authors: treadway jl. J Pharmacol Exp Ther. 2011 Jun;337(3):610-20. doi: 10.1124/jpet.110.177899. Epub 2011 Mar 1. J Pharmacol Exp Ther. 2011. PMID: 21363927 Free PMC article.

2

Defective glycogenesis contributes toward the inability to suppress hepatic glucose production in response to hyperglycemia and hyperinsulinemia in zucker diabetic fatty rats.

Torres TP, Fujimoto Y, Donahue EP, Printz RL, Houseknecht KL, Treadway JL, Shiota M. Torres TP, et al. Among authors: treadway jl. Diabetes. 2011 Sep;60(9):2225-33. doi: 10.2337/db09-1156. Epub 2011 Jul 19. Diabetes. 2011. PMID: 21771972 Free PMC article.

3

Astrocyte glycogen sustains neuronal activity during hypoglycemia: studies with the glycogen phosphorylase inhibitor CP-316,819 ([R-R*,S*]-5-chloro-N-[2-hydroxy-3-(methoxymethylamino)-3-oxo-1-(phenylmethyl)propyl]-1H-indole-2-carboxamide).

Suh SW, Bergher JP, Anderson CM, Treadway JL, Fosgerau K, Swanson RA. Suh SW, et al. Among authors: treadway jl. J Pharmacol Exp Ther. 2007 Apr;321(1):45-50. doi: 10.1124/jpet.106.115550. Epub 2007 Jan 24. J Pharmacol Exp Ther. 2007. PMID: 17251391

4

Establishment of correlation between in vitro enzyme binding potency and in vivo pharmacological activity: application to liver glycogen phosphorylase a inhibitors.

Yu LJ, Chen Y, Treadway JL, McPherson RK, McCoid SC, Gibbs EM, Hoover DJ. Yu LJ, et al. Among authors: treadway jl. J Pharmacol Exp Ther. 2006 Jun;317(3):1230-7. doi: 10.1124/jpet.105.100545. Epub 2006 Mar 14. J Pharmacol Exp Ther. 2006. PMID: 16537796

5

The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug.

Kelsall IR, Munro S, Hallyburton I, Treadway JL, Cohen PT. Kelsall IR, et al. Among authors: treadway jl. FEBS Lett. 2007 Oct 2;581(24):4749-53. doi: 10.1016/j.febslet.2007.08.073. Epub 2007 Sep 6. FEBS Lett. 2007. PMID: 17870073 Free article.

6

Discovery of a human liver glycogen phosphorylase inhibitor that lowers blood glucose in vivo.

Martin WH, Hoover DJ, Armento SJ, Stock IA, McPherson RK, Danley DE, Stevenson RW, Barrett EJ, Treadway JL. Martin WH, et al. Among authors: treadway jl. Proc Natl Acad Sci U S A. 1998 Feb 17;95(4):1776-81. doi: 10.1073/pnas.95.4.1776. Proc Natl Acad Sci U S A. 1998. PMID: 9465093 Free PMC article.

7

Cardioprotective effects of ingliforib, a novel glycogen phosphorylase inhibitor.

Tracey WR, Treadway JL, Magee WP, Sutt JC, McPherson RK, Levy CB, Wilder DE, Yu LJ, Chen Y, Shanker RM, Mutchler AK, Smith AH, Flynn DM, Knight DR. Tracey WR, et al. Among authors: treadway jl. Am J Physiol Heart Circ Physiol. 2004 Mar;286(3):H1177-84. doi: 10.1152/ajpheart.00652.2003. Epub 2003 Nov 13. Am J Physiol Heart Circ Physiol. 2004. PMID: 14615278 Free article.

8

Integrated effects of multiple modulators on human liver glycogen phosphorylase a.

Ercan-Fang N, Gannon MC, Rath VL, Treadway JL, Taylor MR, Nuttall FQ. Ercan-Fang N, et al. Among authors: treadway jl. Am J Physiol Endocrinol Metab. 2002 Jul;283(1):E29-37. doi: 10.1152/ajpendo.00425.2001. Am J Physiol Endocrinol Metab. 2002. PMID: 12067839 Free article.

9

Endogenous effectors of human liver glycogen phosphorylase modulate effects of indole-site inhibitors.

Ercan-Fang N, Taylor MR, Treadway JL, Levy CB, Genereux PE, Gibbs EM, Rath VL, Kwon Y, Gannon MC, Nuttall FQ. Ercan-Fang N, et al. Among authors: treadway jl. Am J Physiol Endocrinol Metab. 2005 Sep;289(3):E366-72. doi: 10.1152/ajpendo.00264.2004. Epub 2005 Mar 29. Am J Physiol Endocrinol Metab. 2005. PMID: 15797986 Free article.

10

Transgenic mice expressing the human GLUT4/muscle-fat facilitative glucose transporter protein exhibit efficient glycemic control.

Liu ML, Gibbs EM, McCoid SC, Milici AJ, Stukenbrok HA, McPherson RK, Treadway JL, Pessin JE. Liu ML, et al. Among authors: treadway jl. Proc Natl Acad Sci U S A. 1993 Dec 1;90(23):11346-50. doi: 10.1073/pnas.90.23.11346. Proc Natl Acad Sci U S A. 1993. PMID: 8248251 Free PMC article.

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