Harrison DJ - Search Results

1

Transcriptionally repressed genes become aberrantly methylated and distinguish tumors of different lineages in breast cancer.

Sproul D, Nestor C, Culley J, Dickson JH, Dixon JM, Harrison DJ, Meehan RR, Sims AH, Ramsahoye BH. Sproul D, et al. Among authors: harrison dj. Proc Natl Acad Sci U S A. 2011 Mar 15;108(11):4364-9. doi: 10.1073/pnas.1013224108. Epub 2011 Feb 28. Proc Natl Acad Sci U S A. 2011. PMID: 21368160 Free PMC article.

2

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes.

Nestor CE, Ottaviano R, Reddington J, Sproul D, Reinhardt D, Dunican D, Katz E, Dixon JM, Harrison DJ, Meehan RR. Nestor CE, et al. Among authors: harrison dj. Genome Res. 2012 Mar;22(3):467-77. doi: 10.1101/gr.126417.111. Epub 2011 Nov 21. Genome Res. 2012. PMID: 22106369 Free PMC article.

3

An in vitro model that recapitulates the epithelial to mesenchymal transition (EMT) in human breast cancer.

Katz E, Dubois-Marshall S, Sims AH, Gautier P, Caldwell H, Meehan RR, Harrison DJ. Katz E, et al. Among authors: harrison dj. PLoS One. 2011 Feb 15;6(2):e17083. doi: 10.1371/journal.pone.0017083. PLoS One. 2011. PMID: 21347235 Free PMC article.

4

Sprouty 2 is an independent prognostic factor in breast cancer and may be useful in stratifying patients for trastuzumab therapy.

Faratian D, Sims AH, Mullen P, Kay C, Um I, Langdon SP, Harrison DJ. Faratian D, et al. Among authors: harrison dj. PLoS One. 2011;6(8):e23772. doi: 10.1371/journal.pone.0023772. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21909357 Free PMC article.

5

Lactate, a product of glycolytic metabolism, inhibits histone deacetylase activity and promotes changes in gene expression.

Latham T, Mackay L, Sproul D, Karim M, Culley J, Harrison DJ, Hayward L, Langridge-Smith P, Gilbert N, Ramsahoye BH. Latham T, et al. Among authors: harrison dj. Nucleic Acids Res. 2012 Jun;40(11):4794-803. doi: 10.1093/nar/gks066. Epub 2012 Feb 9. Nucleic Acids Res. 2012. PMID: 22323521 Free PMC article.

6

Diversity of matriptase expression level and function in breast cancer.

Welman A, Sproul D, Mullen P, Muir M, Kinnaird AR, Harrison DJ, Faratian D, Brunton VG, Frame MC. Welman A, et al. Among authors: harrison dj. PLoS One. 2012;7(4):e34182. doi: 10.1371/journal.pone.0034182. Epub 2012 Apr 13. PLoS One. 2012. PMID: 22514623 Free PMC article.

7

Targeting of Rac GTPases blocks the spread of intact human breast cancer.

Katz E, Sims AH, Sproul D, Caldwell H, Dixon MJ, Meehan RR, Harrison DJ. Katz E, et al. Among authors: harrison dj. Oncotarget. 2012 Jun;3(6):608-19. doi: 10.18632/oncotarget.520. Oncotarget. 2012. PMID: 22689141 Free PMC article.

8

Tissue of origin determines cancer-associated CpG island promoter hypermethylation patterns.

Sproul D, Kitchen RR, Nestor CE, Dixon JM, Sims AH, Harrison DJ, Ramsahoye BH, Meehan RR. Sproul D, et al. Among authors: harrison dj. Genome Biol. 2012 Oct 3;13(10):R84. doi: 10.1186/gb-2012-13-10-r84. Genome Biol. 2012. PMID: 23034185 Free PMC article.

9

Use of microarray analysis to investigate EMT gene signatures.

Sims AH, Larionov AA, Harrison DJ, Katz E. Sims AH, et al. Among authors: harrison dj. Methods Mol Biol. 2013;1046:85-95. doi: 10.1007/978-1-62703-538-5_5. Methods Mol Biol. 2013. PMID: 23868583

10

5-hydroxymethylcytosine profiling as an indicator of cellular state.

Laird A, Thomson JP, Harrison DJ, Meehan RR. Laird A, et al. Among authors: harrison dj. Epigenomics. 2013 Dec;5(6):655-69. doi: 10.2217/epi.13.69. Epigenomics. 2013. PMID: 24283880 Free article. Review.

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