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Sugammadex is cleared rapidly and primarily unchanged via renal excretion.
Peeters P, Passier P, Smeets J, Zwiers A, de Zwart M, van de Wetering-Krebbers S, van Iersel M, van Marle S, van den Dobbelsteen D. Peeters P, et al. Among authors: van de wetering krebbers s. Biopharm Drug Dispos. 2011 Apr;32(3):159-67. doi: 10.1002/bdd.747. Epub 2011 Mar 1. Biopharm Drug Dispos. 2011. PMID: 21370235
Metabolism and excretion of asenapine in healthy male subjects.
van de Wetering-Krebbers SF, Jacobs PL, Kemperman GJ, Spaans E, Peeters PA, Delbressine LP, van Iersel ML. van de Wetering-Krebbers SF, et al. Drug Metab Dispos. 2011 Apr;39(4):580-90. doi: 10.1124/dmd.110.036715. Epub 2010 Dec 22. Drug Metab Dispos. 2011. PMID: 21177986 Clinical Trial.