Frincke JM - Search Results

1

HE3286, an orally bioavailable synthetic analogue of an active DHEA metabolite suppresses spontaneous autoimmune diabetes in the non-obese diabetic (NOD) mouse.

Kosiewicz MM, Auci DL, Fagone P, Mangano K, Caponnetto S, Tucker CF, Azeem N, White SK, Frincke JM, Reading CL, Nicoletti F. Kosiewicz MM, et al. Among authors: frincke jm. Eur J Pharmacol. 2011 May 11;658(2-3):257-62. doi: 10.1016/j.ejphar.2011.02.016. Epub 2011 Mar 1. Eur J Pharmacol. 2011. PMID: 21371458

2

An orally bioavailable synthetic analog of an active dehydroepiandrosterone metabolite reduces established disease in rodent models of rheumatoid arthritis.

Offner H, Firestein GS, Boyle DL, Pieters R, Frincke JM, Garsd A, White SK, Reading CL, Auci DL. Offner H, et al. Among authors: frincke jm. J Pharmacol Exp Ther. 2009 Jun;329(3):1100-9. doi: 10.1124/jpet.108.145086. Epub 2009 Mar 18. J Pharmacol Exp Ther. 2009. PMID: 19297421 Free article.

3

7-Hydroxy androstene steroids and a novel synthetic analogue with reduced side effects as a potential agent to treat autoimmune diseases.

Auci DL, Reading CL, Frincke JM. Auci DL, et al. Among authors: frincke jm. Autoimmun Rev. 2009 Mar;8(5):369-72. doi: 10.1016/j.autrev.2008.11.011. Epub 2008 Dec 9. Autoimmun Rev. 2009. PMID: 19071234 Review.

4

Molecular targets for 17α-ethynyl-5-androstene-3β,7β,17β-triol, an anti-inflammatory agent derived from the human metabolome.

Reading CL, Frincke JM, White SK. Reading CL, et al. Among authors: frincke jm. PLoS One. 2012;7(2):e32147. doi: 10.1371/journal.pone.0032147. Epub 2012 Feb 24. PLoS One. 2012. PMID: 22384159 Free PMC article.

5

Oral treatment with HE3286 ameliorates disease in rodent models of rheumatoid arthritis.

Auci DL, Mangano K, Destiche D, White SK, Huang Y, Boyle D, Frincke J, Reading CL, Nicoletti F. Auci DL, et al. Int J Mol Med. 2010 Apr;25(4):625-33. doi: 10.3892/ijmm_00000385. Int J Mol Med. 2010. PMID: 20198312

6

HE3286: a novel synthetic steroid as an oral treatment for autoimmune disease.

Ahlem C, Auci D, Mangano K, Reading C, Frincke J, Stickney D, Nicoletti F. Ahlem C, et al. Ann N Y Acad Sci. 2009 Sep;1173:781-90. doi: 10.1111/j.1749-6632.2009.04798.x. Ann N Y Acad Sci. 2009. PMID: 19758229

7

A new orally bioavailable synthetic androstene inhibits collagen-induced arthritis in the mouse: androstene hormones as regulators of regulatory T cells.

Auci D, Kaler L, Subramanian S, Huang Y, Frincke J, Reading C, Offner H. Auci D, et al. Ann N Y Acad Sci. 2007 Sep;1110:630-40. doi: 10.1196/annals.1423.066. Ann N Y Acad Sci. 2007. PMID: 17911478

8

HE3286, an oral synthetic steroid, treats lung inflammation in mice without immune suppression.

Conrad D, Wang A, Pieters R, Nicoletti F, Mangano K, van Heeckeren AM, White SK, Frincke JM, Reading CL, Stickney D, Auci DL. Conrad D, et al. Among authors: frincke jm. J Inflamm (Lond). 2010 Oct 30;7:52. doi: 10.1186/1476-9255-7-52. J Inflamm (Lond). 2010. PMID: 21034489 Free PMC article.

9

Pharmacology and immune modulating properties of 5-androstene-3β,7β,17β-triol, a DHEA metabolite in the human metabolome.

Ahlem CN, Auci DL, Nicoletti F, Pieters R, Kennedy MR, Page TM, Reading CL, Enioutina EY, Frincke JM. Ahlem CN, et al. Among authors: frincke jm. J Steroid Biochem Mol Biol. 2011 Sep;126(3-5):87-94. doi: 10.1016/j.jsbmb.2011.04.010. Epub 2011 May 5. J Steroid Biochem Mol Biol. 2011. PMID: 21570467

10

17α-Ethynyl-androst-5-ene-3β,7β,17β-triol (HE3286) Is Neuroprotective and Reduces Motor Impairment and Neuroinflammation in a Murine MPTP Model of Parkinson's Disease.

Nicoletti F, Philippens I, Fagone P, Ahlem CN, Reading CL, Frincke JM, Auci DL. Nicoletti F, et al. Among authors: frincke jm. Parkinsons Dis. 2012;2012:969418. doi: 10.1155/2012/969418. Epub 2012 Sep 26. Parkinsons Dis. 2012. PMID: 23050197 Free PMC article.

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