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The cerebrospinal fluid provides a proliferative niche for neural progenitor cells.
Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA. Lehtinen MK, et al. Among authors: chen x. Neuron. 2011 Mar 10;69(5):893-905. doi: 10.1016/j.neuron.2011.01.023. Neuron. 2011. PMID: 21382550 Free PMC article.
Discovery of First Branched-Chain Ketoacid Dehydrogenase Kinase (BDK) Inhibitor Clinical Candidate PF-07328948.
Filipski KJ, Martinez-Alsina LA, Reese MR, Evrard E, Buzon LM, Cameron KO, Zhang Y, Coffman KJ, Bradow J, Kormos BL, Liu S, Knafels JD, Sahasrabudhe PV, Chen J, Kalgutkar AS, Bessire AJ, Orozco CC, Balesano A, Cerny MA, Bollinger E, Reyes AR, Laforest B, Rosado A, Williams G, Marshall M, Tam Neale K, Chen X, Hirenallur-Shanthappa D, Stansfield JC, Groarke J, Qiu R, Karas S, Roth Flach RJ, Esler WP. Filipski KJ, et al. Among authors: chen x. J Med Chem. 2024 Nov 19. doi: 10.1021/acs.jmedchem.4c02230. Online ahead of print. J Med Chem. 2024. PMID: 39560668
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