Munn DH - Search Results

1

Coexpression of Tim-3 and PD-1 identifies a CD8+ T-cell exhaustion phenotype in mice with disseminated acute myelogenous leukemia.

Zhou Q, Munger ME, Veenstra RG, Weigel BJ, Hirashima M, Munn DH, Murphy WJ, Azuma M, Anderson AC, Kuchroo VK, Blazar BR. Zhou Q, et al. Among authors: munn dh. Blood. 2011 Apr 28;117(17):4501-10. doi: 10.1182/blood-2010-10-310425. Epub 2011 Mar 8. Blood. 2011. PMID: 21385853 Free PMC article.

2

Plasmacytoid dendritic cells from mouse tumor-draining lymph nodes directly activate mature Tregs via indoleamine 2,3-dioxygenase.

Sharma MD, Baban B, Chandler P, Hou DY, Singh N, Yagita H, Azuma M, Blazar BR, Mellor AL, Munn DH. Sharma MD, et al. Among authors: munn dh. J Clin Invest. 2007 Sep;117(9):2570-82. doi: 10.1172/JCI31911. J Clin Invest. 2007. PMID: 17710230 Free PMC article.

3

Indoleamine 2,3-dioxygenase is a critical regulator of acute graft-versus-host disease lethality.

Jasperson LK, Bucher C, Panoskaltsis-Mortari A, Taylor PA, Mellor AL, Munn DH, Blazar BR. Jasperson LK, et al. Among authors: munn dh. Blood. 2008 Mar 15;111(6):3257-65. doi: 10.1182/blood-2007-06-096081. Epub 2007 Dec 12. Blood. 2008. PMID: 18077788 Free PMC article.

4

The indoleamine 2,3-dioxygenase pathway is essential for human plasmacytoid dendritic cell-induced adaptive T regulatory cell generation.

Chen W, Liang X, Peterson AJ, Munn DH, Blazar BR. Chen W, et al. Among authors: munn dh. J Immunol. 2008 Oct 15;181(8):5396-404. doi: 10.4049/jimmunol.181.8.5396. J Immunol. 2008. PMID: 18832696 Free PMC article.

5

Depletion of endogenous tumor-associated regulatory T cells improves the efficacy of adoptive cytotoxic T-cell immunotherapy in murine acute myeloid leukemia.

Zhou Q, Bucher C, Munger ME, Highfill SL, Tolar J, Munn DH, Levine BL, Riddle M, June CH, Vallera DA, Weigel BJ, Blazar BR. Zhou Q, et al. Among authors: munn dh. Blood. 2009 Oct 29;114(18):3793-802. doi: 10.1182/blood-2009-03-208181. Epub 2009 Sep 1. Blood. 2009. PMID: 19724059 Free PMC article.

6

Inducing the tryptophan catabolic pathway, indoleamine 2,3-dioxygenase (IDO), for suppression of graft-versus-host disease (GVHD) lethality.

Jasperson LK, Bucher C, Panoskaltsis-Mortari A, Mellor AL, Munn DH, Blazar BR. Jasperson LK, et al. Among authors: munn dh. Blood. 2009 Dec 3;114(24):5062-70. doi: 10.1182/blood-2009-06-227587. Epub 2009 Oct 14. Blood. 2009. PMID: 19828695 Free PMC article.

7

Chemotherapy rescues tumor-driven aberrant CD4+ T-cell differentiation and restores an activated polyfunctional helper phenotype.

Ding ZC, Blazar BR, Mellor AL, Munn DH, Zhou G. Ding ZC, et al. Among authors: munn dh. Blood. 2010 Mar 25;115(12):2397-406. doi: 10.1182/blood-2009-11-253336. Epub 2010 Jan 29. Blood. 2010. PMID: 20118405 Free PMC article.

8

Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

Zhou Q, Munger ME, Highfill SL, Tolar J, Weigel BJ, Riddle M, Sharpe AH, Vallera DA, Azuma M, Levine BL, June CH, Murphy WJ, Munn DH, Blazar BR. Zhou Q, et al. Among authors: munn dh. Blood. 2010 Oct 7;116(14):2484-93. doi: 10.1182/blood-2010-03-275446. Epub 2010 Jun 22. Blood. 2010. PMID: 20570856 Free PMC article.

9

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13.

Highfill SL, Rodriguez PC, Zhou Q, Goetz CA, Koehn BH, Veenstra R, Taylor PA, Panoskaltsis-Mortari A, Serody JS, Munn DH, Tolar J, Ochoa AC, Blazar BR. Highfill SL, et al. Among authors: munn dh. Blood. 2010 Dec 16;116(25):5738-47. doi: 10.1182/blood-2010-06-287839. Epub 2010 Aug 31. Blood. 2010. PMID: 20807889 Free PMC article.

10

Reprogrammed foxp3(+) regulatory T cells provide essential help to support cross-presentation and CD8(+) T cell priming in naive mice.

Sharma MD, Hou DY, Baban B, Koni PA, He Y, Chandler PR, Blazar BR, Mellor AL, Munn DH. Sharma MD, et al. Among authors: munn dh. Immunity. 2010 Dec 14;33(6):942-54. doi: 10.1016/j.immuni.2010.11.022. Epub 2010 Dec 9. Immunity. 2010. PMID: 21145762 Free PMC article.

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