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ST-246 antiviral efficacy in a nonhuman primate monkeypox model: determination of the minimal effective dose and human dose justification.
Jordan R, Goff A, Frimm A, Corrado ML, Hensley LE, Byrd CM, Mucker E, Shamblin J, Bolken TC, Wlazlowski C, Johnson W, Chapman J, Twenhafel N, Tyavanagimatt S, Amantana A, Chinsangaram J, Hruby DE, Huggins J. Jordan R, et al. Among authors: chapman j. Antimicrob Agents Chemother. 2009 May;53(5):1817-22. doi: 10.1128/AAC.01596-08. Epub 2009 Feb 17. Antimicrob Agents Chemother. 2009. PMID: 19223621 Free PMC article. Clinical Trial.
Nonhuman primates are protected from smallpox virus or monkeypox virus challenges by the antiviral drug ST-246.
Huggins J, Goff A, Hensley L, Mucker E, Shamblin J, Wlazlowski C, Johnson W, Chapman J, Larsen T, Twenhafel N, Karem K, Damon IK, Byrd CM, Bolken TC, Jordan R, Hruby D. Huggins J, et al. Among authors: chapman j. Antimicrob Agents Chemother. 2009 Jun;53(6):2620-5. doi: 10.1128/AAC.00021-09. Epub 2009 Apr 6. Antimicrob Agents Chemother. 2009. PMID: 19349521 Free PMC article.
Animal models of orthopoxvirus infection.
Chapman JL, Nichols DK, Martinez MJ, Raymond JW. Chapman JL, et al. Vet Pathol. 2010 Sep;47(5):852-70. doi: 10.1177/0300985810378649. Epub 2010 Aug 3. Vet Pathol. 2010. PMID: 20682806 Review.
The pathogenesis of Rift Valley fever virus in the mouse model.
Smith DR, Steele KE, Shamblin J, Honko A, Johnson J, Reed C, Kennedy M, Chapman JL, Hensley LE. Smith DR, et al. Among authors: chapman jl. Virology. 2010 Nov 25;407(2):256-67. doi: 10.1016/j.virol.2010.08.016. Epub 2010 Sep 17. Virology. 2010. PMID: 20850165 Free article.
4,288 results