Takeuchi T - Search Results

1

A study comparing the antisecretory effect of TAK-438, a novel potassium-competitive acid blocker, with lansoprazole in animals.

Hori Y, Matsukawa J, Takeuchi T, Nishida H, Kajino M, Inatomi N. Hori Y, et al. Among authors: takeuchi t. J Pharmacol Exp Ther. 2011 Jun;337(3):797-804. doi: 10.1124/jpet.111.179556. Epub 2011 Mar 16. J Pharmacol Exp Ther. 2011. PMID: 21411494

2

Discovery of a novel pyrrole derivative 1-[5-(2-fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine fumarate (TAK-438) as a potassium-competitive acid blocker (P-CAB).

Arikawa Y, Nishida H, Kurasawa O, Hasuoka A, Hirase K, Inatomi N, Hori Y, Matsukawa J, Imanishi A, Kondo M, Tarui N, Hamada T, Takagi T, Takeuchi T, Kajino M. Arikawa Y, et al. Among authors: takeuchi t. J Med Chem. 2012 May 10;55(9):4446-56. doi: 10.1021/jm300318t. Epub 2012 Apr 30. J Med Chem. 2012. PMID: 22512618

3

Disposition and metabolism of TAK-438 (vonoprazan fumarate), a novel potassium-competitive acid blocker, in rats and dogs.

Kogame A, Takeuchi T, Nonaka M, Yamasaki H, Kawaguchi N, Bernards A, Tagawa Y, Morohashi A, Kondo T, Moriwaki T, Asahi S. Kogame A, et al. Among authors: takeuchi t. Xenobiotica. 2017 Mar;47(3):255-266. doi: 10.1080/00498254.2016.1182667. Epub 2016 May 26. Xenobiotica. 2017. PMID: 27225050

4

Effect of a novel 17,20-lyase inhibitor, orteronel (TAK-700), on androgen synthesis in male rats.

Hara T, Kouno J, Kaku T, Takeuchi T, Kusaka M, Tasaka A, Yamaoka M. Hara T, et al. Among authors: takeuchi t. J Steroid Biochem Mol Biol. 2013 Mar;134:80-91. doi: 10.1016/j.jsbmb.2012.10.020. Epub 2012 Nov 9. J Steroid Biochem Mol Biol. 2013. PMID: 23146910

5

Absorption of TAK-491, a new angiotensin II receptor antagonist, in animals.

Kawaguchi N, Ebihara T, Takeuchi T, Morohashi A, Yamasaki H, Tagawa Y, Takahashi J, Kondo T, Asahi S. Kawaguchi N, et al. Among authors: takeuchi t. Xenobiotica. 2013 Feb;43(2):182-92. doi: 10.3109/00498254.2012.708797. Epub 2012 Aug 7. Xenobiotica. 2013. PMID: 22867273

6

Marked impact of P-glycoprotein on the absorption of TAK-427 in rats.

Takeuchi T, Nonaka M, Yoshitomi S, Higuchi T, Ebihara T, Maeshiba Y, Kawase M, Asahi S. Takeuchi T, et al. Biopharm Drug Dispos. 2008 Sep;29(6):311-23. doi: 10.1002/bdd.609. Biopharm Drug Dispos. 2008. PMID: 18651556

7

Investigation of the unique metabolic fate of ethyl (6R)-6- [N- (2-chloro-4-fluorophenyl) sulfamoyl] cyclohex-1-ene-1-carboxylate (TAK-242) in rats and dogs using two types of 14C-labeled compounds having different labeled positions.

Jinno F, Kakehi M, Takeuchi T, Tagawa Y, Kondo T, Asahi S. Jinno F, et al. Among authors: takeuchi t. Arzneimittelforschung. 2011;61(8):458-71. doi: 10.1055/s-0031-1296228. Arzneimittelforschung. 2011. PMID: 21950150

8

Mechanism for Covalent Binding of MLN3126, an Oral Chemokine C-C Motif Receptor 9 Antagonist, to Serum Albumins.

Narita N, Morohashi A, Tohyama K, Takeuchi T, Tagawa Y, Kondo T, Asahi S. Narita N, et al. Among authors: takeuchi t. Drug Metab Dispos. 2018 Mar;46(3):204-213. doi: 10.1124/dmd.117.078782. Epub 2017 Dec 21. Drug Metab Dispos. 2018. PMID: 29269409

9

Pharmacokinetics and Urinary Excretion Mechanism of Orteronel (TAK-700), A Novel 17,20-Lyase Inhibitor, in Animals.

Goto A, Moriya Y, Takeuchi T, Mandai T, Tagawa Y, Kondo T, Asahi S. Goto A, et al. Among authors: takeuchi t. Drug Res (Stuttg). 2016 Apr;66(4):217-22. doi: 10.1055/s-0035-1564118. Epub 2015 Sep 29. Drug Res (Stuttg). 2016. PMID: 26418412

10

Disposition of TAK-044, a new endothelin antagonist, in rats and dogs.

Maeshiba Y, Takeuchi T, Kondo T, Yamashita K, Tsukuda R, Yoshimura Y. Maeshiba Y, et al. Among authors: takeuchi t. Arzneimittelforschung. 2002;52(8):587-92. doi: 10.1055/s-0031-1299935. Arzneimittelforschung. 2002. PMID: 12236045

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