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Redirection of T cells with a first fully humanized bispecific CD33-CD3 antibody efficiently eliminates AML blasts without harming hematopoietic stem cells.
Arndt C, von Bonin M, Cartellieri M, Feldmann A, Koristka S, Michalk I, Stamova S, Bornhäuser M, Schmitz M, Ehninger G, Bachmann M. Arndt C, et al. Among authors: ehninger g. Leukemia. 2013 Apr;27(4):964-7. doi: 10.1038/leu.2013.18. Epub 2013 Jan 17. Leukemia. 2013. PMID: 23325142 No abstract available.
Costimulation improves the killing capability of T cells redirected to tumor cells expressing low levels of CD33: description of a novel modular targeting system.
Arndt C, Feldmann A, von Bonin M, Cartellieri M, Ewen EM, Koristka S, Michalk I, Stamova S, Berndt N, Gocht A, Bornhäuser M, Ehninger G, Schmitz M, Bachmann M. Arndt C, et al. Among authors: ehninger g. Leukemia. 2014 Jan;28(1):59-69. doi: 10.1038/leu.2013.243. Epub 2013 Aug 20. Leukemia. 2014. PMID: 23958923
Infusion of bcr/abl peptide-reactive donor T cells to achieve molecular remission of chronic myeloid leukemia after CD34+ selected allogeneic hematopoietic cell transplantation.
Bornhauser M, Thiede C, Babatz J, Schetelig J, Illmer T, Kiani A, Platzbecker U, Herr W, Rieber EP, Ehninger G, Schmitz M. Bornhauser M, et al. Among authors: ehninger g. Leukemia. 2006 Nov;20(11):2055-7. doi: 10.1038/sj.leu.2404383. Epub 2006 Aug 31. Leukemia. 2006. PMID: 16990776 No abstract available.
815 results