Giacomini KM - Search Results

1

Vorinostat increases expression of functional norepinephrine transporter in neuroblastoma in vitro and in vivo model systems.

More SS, Itsara M, Yang X, Geier EG, Tadano MK, Seo Y, Vanbrocklin HF, Weiss WA, Mueller S, Haas-Kogan DA, Dubois SG, Matthay KK, Giacomini KM. More SS, et al. Among authors: giacomini km. Clin Cancer Res. 2011 Apr 15;17(8):2339-49. doi: 10.1158/1078-0432.CCR-10-2949. Epub 2011 Mar 18. Clin Cancer Res. 2011. PMID: 21421857 Free PMC article.

2

Organic cation transporters are determinants of oxaliplatin cytotoxicity.

Zhang S, Lovejoy KS, Shima JE, Lagpacan LL, Shu Y, Lapuk A, Chen Y, Komori T, Gray JW, Chen X, Lippard SJ, Giacomini KM. Zhang S, et al. Among authors: giacomini km. Cancer Res. 2006 Sep 1;66(17):8847-57. doi: 10.1158/0008-5472.CAN-06-0769. Cancer Res. 2006. PMID: 16951202 Free PMC article.

3

Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP.

Cropp CD, Komori T, Shima JE, Urban TJ, Yee SW, More SS, Giacomini KM. Cropp CD, et al. Among authors: giacomini km. Mol Pharmacol. 2008 Apr;73(4):1151-8. doi: 10.1124/mol.107.043117. Epub 2008 Jan 23. Mol Pharmacol. 2008. PMID: 18216183 Free PMC article.

4

Organic cation transporters modulate the uptake and cytotoxicity of picoplatin, a third-generation platinum analogue.

More SS, Li S, Yee SW, Chen L, Xu Z, Jablons DM, Giacomini KM. More SS, et al. Among authors: giacomini km. Mol Cancer Ther. 2010 Apr;9(4):1058-69. doi: 10.1158/1535-7163.MCT-09-1084. Epub 2010 Apr 6. Mol Cancer Ther. 2010. PMID: 20371711 Free PMC article.

5

Role of the copper transporter, CTR1, in platinum-induced ototoxicity.

More SS, Akil O, Ianculescu AG, Geier EG, Lustig LR, Giacomini KM. More SS, et al. Among authors: giacomini km. J Neurosci. 2010 Jul 14;30(28):9500-9. doi: 10.1523/JNEUROSCI.1544-10.2010. J Neurosci. 2010. PMID: 20631178 Free PMC article.

6

Role of organic cation transporter 3 (SLC22A3) and its missense variants in the pharmacologic action of metformin.

Chen L, Pawlikowski B, Schlessinger A, More SS, Stryke D, Johns SJ, Portman MA, Chen E, Ferrin TE, Sali A, Giacomini KM. Chen L, et al. Among authors: giacomini km. Pharmacogenet Genomics. 2010 Nov;20(11):687-99. doi: 10.1097/FPC.0b013e32833fe789. Pharmacogenet Genomics. 2010. PMID: 20859243 Free PMC article.

7

Role of organic cation transporter 1, OCT1 in the pharmacokinetics and toxicity of cis-diammine(pyridine)chloroplatinum(II) and oxaliplatin in mice.

Li S, Chen Y, Zhang S, More SS, Huang X, Giacomini KM. Li S, et al. Among authors: giacomini km. Pharm Res. 2011 Mar;28(3):610-25. doi: 10.1007/s11095-010-0312-6. Epub 2010 Nov 23. Pharm Res. 2011. PMID: 21104302 Free PMC article.

8

Structure-based discovery of prescription drugs that interact with the norepinephrine transporter, NET.

Schlessinger A, Geier E, Fan H, Irwin JJ, Shoichet BK, Giacomini KM, Sali A. Schlessinger A, et al. Among authors: giacomini km. Proc Natl Acad Sci U S A. 2011 Sep 20;108(38):15810-5. doi: 10.1073/pnas.1106030108. Epub 2011 Sep 1. Proc Natl Acad Sci U S A. 2011. PMID: 21885739 Free PMC article.

9

Evaluation of Norepinephrine Transporter Expression and Metaiodobenzylguanidine Avidity in Neuroblastoma: A Report from the Children's Oncology Group.

Dubois SG, Geier E, Batra V, Yee SW, Neuhaus J, Segal M, Martinez D, Pawel B, Yanik G, Naranjo A, London WB, Kreissman S, Baker D, Attiyeh E, Hogarty MD, Maris JM, Giacomini K, Matthay KK. Dubois SG, et al. Int J Mol Imaging. 2012;2012:250834. doi: 10.1155/2012/250834. Epub 2012 Sep 25. Int J Mol Imaging. 2012. PMID: 23050139 Free PMC article.

10

Gene expression profiling of transporters in the solute carrier and ATP-binding cassette superfamilies in human eye substructures.

Dahlin A, Geier E, Stocker SL, Cropp CD, Grigorenko E, Bloomer M, Siegenthaler J, Xu L, Basile AS, Tang-Liu DD, Giacomini KM. Dahlin A, et al. Among authors: giacomini km. Mol Pharm. 2013 Feb 4;10(2):650-63. doi: 10.1021/mp300429e. Epub 2013 Jan 24. Mol Pharm. 2013. PMID: 23268600 Free PMC article.

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