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RNA interference for viral infections.
Blake SJ, Bokhari FF, McMillan NA. Blake SJ, et al. Curr Drug Targets. 2012 Oct;13(11):1411-20. doi: 10.2174/138945012803530161. Curr Drug Targets. 2012. PMID: 22664094 Review.
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells.
Gao Y, Souza-Fonseca-Guimaraes F, Bald T, Ng SS, Young A, Ngiow SF, Rautela J, Straube J, Waddell N, Blake SJ, Yan J, Bartholin L, Lee JS, Vivier E, Takeda K, Messaoudene M, Zitvogel L, Teng MWL, Belz GT, Engwerda CR, Huntington ND, Nakamura K, Hölzel M, Smyth MJ. Gao Y, et al. Among authors: blake sj. Nat Immunol. 2017 Sep;18(9):1004-1015. doi: 10.1038/ni.3800. Epub 2017 Jul 31. Nat Immunol. 2017. PMID: 28759001
CD96 Is an Immune Checkpoint That Regulates CD8+ T-cell Antitumor Function.
Mittal D, Lepletier A, Madore J, Aguilera AR, Stannard K, Blake SJ, Whitehall VLJ, Liu C, Bettington ML, Takeda K, Long GV, Scolyer RA, Lan R, Siemers N, Korman A, Teng MWL, Johnston RJ, Dougall WC, Smyth MJ. Mittal D, et al. Among authors: blake sj. Cancer Immunol Res. 2019 Apr;7(4):559-571. doi: 10.1158/2326-6066.CIR-18-0637. Epub 2019 Mar 20. Cancer Immunol Res. 2019. PMID: 30894377 Free PMC article.
Deficiency of host CD96 and PD-1 or TIGIT enhances tumor immunity without significantly compromising immune homeostasis.
Harjunpää H, Blake SJ, Ahern E, Allen S, Liu J, Yan J, Lutzky V, Takeda K, Aguilera AR, Guillerey C, Mittal D, Li XY, Dougall WC, Smyth MJ, Teng MWL. Harjunpää H, et al. Among authors: blake sj. Oncoimmunology. 2018 Mar 26;7(7):e1445949. doi: 10.1080/2162402X.2018.1445949. eCollection 2018. Oncoimmunology. 2018. PMID: 29900061 Free PMC article.
The immunotoxicity, but not anti-tumor efficacy, of anti-CD40 and anti-CD137 immunotherapies is dependent on the gut microbiota.
Blake SJ, James J, Ryan FJ, Caparros-Martin J, Eden GL, Tee YC, Salamon JR, Benson SC, Tumes DJ, Sribnaia A, Stevens NE, Finnie JW, Kobayashi H, White DL, Wesselingh SL, O'Gara F, Lynn MA, Lynn DJ. Blake SJ, et al. Cell Rep Med. 2021 Dec 8;2(12):100464. doi: 10.1016/j.xcrm.2021.100464. eCollection 2021 Dec 21. Cell Rep Med. 2021. PMID: 35028606 Free PMC article.
Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy.
Blake SJ, Stannard K, Liu J, Allen S, Yong MC, Mittal D, Aguilera AR, Miles JJ, Lutzky VP, de Andrade LF, Martinet L, Colonna M, Takeda K, Kühnel F, Gurlevik E, Bernhardt G, Teng MW, Smyth MJ. Blake SJ, et al. Cancer Discov. 2016 Apr;6(4):446-59. doi: 10.1158/2159-8290.CD-15-0944. Epub 2016 Jan 19. Cancer Discov. 2016. PMID: 26787820
86 results