Safford RJ - Search Results

1

Refinement of the Dermal Sensitisation Threshold (DST) approach using a larger dataset and incorporating mechanistic chemistry domains.

Safford RJ, Aptula AO, Gilmour N. Safford RJ, et al. Regul Toxicol Pharmacol. 2011 Jul;60(2):218-24. doi: 10.1016/j.yrtph.2011.03.009. Epub 2011 Apr 3. Regul Toxicol Pharmacol. 2011. PMID: 21447365

2

The Dermal Sensitisation Threshold- a TTC approach for allergic contact dermatitis.

Safford RJ. Safford RJ. Regul Toxicol Pharmacol. 2008 Jul;51(2):195-200. doi: 10.1016/j.yrtph.2008.02.010. Epub 2008 Mar 18. Regul Toxicol Pharmacol. 2008. PMID: 18406502

3

Principles for identification of High Potency Category Chemicals for which the Dermal Sensitisation Threshold (DST) approach should not be applied.

Roberts DW, Api AM, Safford RJ, Lalko JF. Roberts DW, et al. Among authors: safford rj. Regul Toxicol Pharmacol. 2015 Aug;72(3):683-93. doi: 10.1016/j.yrtph.2015.03.001. Epub 2015 Mar 9. Regul Toxicol Pharmacol. 2015. PMID: 25765509

4

Extension of the Dermal Sensitisation Threshold (DST) approach to incorporate chemicals classified as reactive.

Safford RJ, Api AM, Roberts DW, Lalko JF. Safford RJ, et al. Regul Toxicol Pharmacol. 2015 Aug;72(3):694-701. doi: 10.1016/j.yrtph.2015.04.020. Epub 2015 Apr 29. Regul Toxicol Pharmacol. 2015. PMID: 25934255

5

Application of the dermal sensitization threshold concept to chemicals classified as high potency category for skin sensitization assessment of ingredients for consumer products.

Nishijo T, Api AM, Gerberick GF, Miyazawa M, Roberts DW, Safford RJ, Sakaguchi H. Nishijo T, et al. Among authors: safford rj. Regul Toxicol Pharmacol. 2020 Nov;117:104732. doi: 10.1016/j.yrtph.2020.104732. Epub 2020 Aug 11. Regul Toxicol Pharmacol. 2020. PMID: 32795584

6

Dermal sensitization quantitative risk assessment (QRA) for fragrance ingredients.

Api AM, Basketter DA, Cadby PA, Cano MF, Ellis G, Gerberick GF, Griem P, McNamee PM, Ryan CA, Safford R. Api AM, et al. Regul Toxicol Pharmacol. 2008 Oct;52(1):3-23. doi: 10.1016/j.yrtph.2007.10.008. Epub 2007 Oct 24. Regul Toxicol Pharmacol. 2008. PMID: 18406028 Review.

7

Updating the Dermal Sensitisation Thresholds using an expanded dataset and an in silico expert system.

Chilton ML, Api AM, Foster RS, Gerberick GF, Lavelle M, Macmillan DS, Na M, O'Brien D, O'Leary-Steele C, Patel M, Ponting DJ, Roberts DW, Safford RJ, Tennant RE. Chilton ML, et al. Among authors: safford rj. Regul Toxicol Pharmacol. 2022 Aug;133:105200. doi: 10.1016/j.yrtph.2022.105200. Epub 2022 Jun 1. Regul Toxicol Pharmacol. 2022. PMID: 35662638 Free article.

8

Immediate contact reactions to chemicals in the fragrance mix and a study of the quenching action of eugenol.

Safford RJ, Basketter DA, Allenby CF, Goodwin BF. Safford RJ, et al. Br J Dermatol. 1990 Nov;123(5):595-606. doi: 10.1111/j.1365-2133.1990.tb01476.x. Br J Dermatol. 1990. PMID: 2248889

9

An evaluation of the implementation of the Cramer classification scheme in the Toxtree software.

Patlewicz G, Jeliazkova N, Safford RJ, Worth AP, Aleksiev B. Patlewicz G, et al. Among authors: safford rj. SAR QSAR Environ Res. 2008;19(5-6):495-524. doi: 10.1080/10629360802083871. SAR QSAR Environ Res. 2008. PMID: 18853299

10

Diminution of immediate reactions to cinnamic aldehyde by eugenol.

Allenby CF, Goodwin BF, Safford RJ. Allenby CF, et al. Among authors: safford rj. Contact Dermatitis. 1984 Nov;11(5):322-3. doi: 10.1111/j.1600-0536.1984.tb01025.x. Contact Dermatitis. 1984. PMID: 6525828 No abstract available.

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