Würstle ML - Search Results

1

Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.

Laussmann MA, Passante E, Düssmann H, Rauen JA, Würstle ML, Delgado ME, Devocelle M, Prehn JH, Rehm M. Laussmann MA, et al. Among authors: wurstle ml. Cell Death Differ. 2011 Oct;18(10):1584-97. doi: 10.1038/cdd.2011.27. Epub 2011 Apr 1. Cell Death Differ. 2011. PMID: 21455219 Free PMC article.

2

Systems analysis of apoptosis protein expression allows the case-specific prediction of cell death responsiveness of melanoma cells.

Passante E, Würstle ML, Hellwig CT, Leverkus M, Rehm M. Passante E, et al. Among authors: wurstle ml. Cell Death Differ. 2013 Nov;20(11):1521-31. doi: 10.1038/cdd.2013.106. Epub 2013 Aug 9. Cell Death Differ. 2013. PMID: 23933815 Free PMC article.

3

The caspase-8 dimerization/dissociation balance is a highly potent regulator of caspase-8, -3, -6 signaling.

Würstle ML, Laussmann MA, Rehm M. Würstle ML, et al. J Biol Chem. 2010 Oct 22;285(43):33209-33218. doi: 10.1074/jbc.M110.113860. Epub 2010 Aug 11. J Biol Chem. 2010. PMID: 20702410 Free PMC article.

4

The central role of initiator caspase-9 in apoptosis signal transduction and the regulation of its activation and activity on the apoptosome.

Würstle ML, Laussmann MA, Rehm M. Würstle ML, et al. Exp Cell Res. 2012 Jul 1;318(11):1213-20. doi: 10.1016/j.yexcr.2012.02.013. Epub 2012 Feb 28. Exp Cell Res. 2012. PMID: 22406265 Review.

5

Single-cell quantification of Bax activation and mathematical modelling suggest pore formation on minimal mitochondrial Bax accumulation.

Düssmann H, Rehm M, Concannon CG, Anguissola S, Würstle M, Kacmar S, Völler P, Huber HJ, Prehn JH. Düssmann H, et al. Cell Death Differ. 2010 Feb;17(2):278-90. doi: 10.1038/cdd.2009.123. Epub 2009 Sep 11. Cell Death Differ. 2010. PMID: 19745831

6

From computational modelling of the intrinsic apoptosis pathway to a systems-based analysis of chemotherapy resistance: achievements, perspectives and challenges in systems medicine.

Würstle ML, Zink E, Prehn JH, Rehm M. Würstle ML, et al. Cell Death Dis. 2014 May 29;5(5):e1258. doi: 10.1038/cddis.2014.36. Cell Death Dis. 2014. PMID: 24874730 Free PMC article. Review.

7

A systems biology analysis of apoptosome formation and apoptosis execution supports allosteric procaspase-9 activation.

Würstle ML, Rehm M. Würstle ML, et al. J Biol Chem. 2014 Sep 19;289(38):26277-26289. doi: 10.1074/jbc.M114.590034. Epub 2014 Aug 8. J Biol Chem. 2014. PMID: 25107908 Free PMC article.

8

An Analysis of the Truncated Bid- and ROS-dependent Spatial Propagation of Mitochondrial Permeabilization Waves during Apoptosis.

Jacob SF, Würstle ML, Delgado ME, Rehm M. Jacob SF, et al. Among authors: wurstle ml. J Biol Chem. 2016 Feb 26;291(9):4603-13. doi: 10.1074/jbc.M115.689109. Epub 2015 Dec 23. J Biol Chem. 2016. PMID: 26699404 Free PMC article.

9

A Stepwise Integrated Approach to Personalized Risk Predictions in Stage III Colorectal Cancer.

Salvucci M, Würstle ML, Morgan C, Curry S, Cremona M, Lindner AU, Bacon O, Resler AJ, Murphy ÁC, O'Byrne R, Flanagan L, Dasgupta S, Rice N, Pilati C, Zink E, Schöller LM, Toomey S, Lawler M, Johnston PG, Wilson R, Camilleri-Broët S, Salto-Tellez M, McNamara DA, Kay EW, Laurent-Puig P, Van Schaeybroeck S, Hennessy BT, Longley DB, Rehm M, Prehn JH. Salvucci M, et al. Among authors: wurstle ml. Clin Cancer Res. 2017 Mar 1;23(5):1200-1212. doi: 10.1158/1078-0432.CCR-16-1084. Epub 2016 Sep 20. Clin Cancer Res. 2017. PMID: 27649552

10

Predicting the cell death responsiveness and sensitization of glioma cells to TRAIL and temozolomide.

Weyhenmeyer BC, Noonan J, Würstle ML, Lincoln FA, Johnston G, Rehm M, Murphy BM. Weyhenmeyer BC, et al. Among authors: wurstle ml. Oncotarget. 2016 Sep 20;7(38):61295-61311. doi: 10.18632/oncotarget.10973. Oncotarget. 2016. PMID: 27494880 Free PMC article.

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