Hennighausen L - Search Results

1

Direct activation of STAT5 by ETV6-LYN fusion protein promotes induction of myeloproliferative neoplasm with myelofibrosis.

Takeda Y, Nakaseko C, Tanaka H, Takeuchi M, Yui M, Saraya A, Miyagi S, Wang C, Tanaka S, Ohwada C, Sakaida E, Yamaguchi N, Yokote K, Hennighausen L, Iwama A. Takeda Y, et al. Among authors: hennighausen l. Br J Haematol. 2011 Jun;153(5):589-98. doi: 10.1111/j.1365-2141.2011.08663.x. Epub 2011 Apr 15. Br J Haematol. 2011. PMID: 21492125 Free PMC article.

2

Tumor suppression by phospholipase C-beta3 via SHP-1-mediated dephosphorylation of Stat5.

Xiao W, Hong H, Kawakami Y, Kato Y, Wu D, Yasudo H, Kimura A, Kubagawa H, Bertoli LF, Davis RS, Chau LA, Madrenas J, Hsia CC, Xenocostas A, Kipps TJ, Hennighausen L, Iwama A, Nakauchi H, Kawakami T. Xiao W, et al. Among authors: hennighausen l. Cancer Cell. 2009 Aug 4;16(2):161-71. doi: 10.1016/j.ccr.2009.05.018. Cancer Cell. 2009. PMID: 19647226 Free PMC article.

3

Hepatocyte-specific disruption of Bcl-xL leads to continuous hepatocyte apoptosis and liver fibrotic responses.

Takehara T, Tatsumi T, Suzuki T, Rucker EB 3rd, Hennighausen L, Jinushi M, Miyagi T, Kanazawa Y, Hayashi N. Takehara T, et al. Among authors: hennighausen l. Gastroenterology. 2004 Oct;127(4):1189-97. doi: 10.1053/j.gastro.2004.07.019. Gastroenterology. 2004. PMID: 15480996

4

Myeloproliferative disease induced by TEL-PDGFRB displays dynamic range sensitivity to Stat5 gene dosage.

Cain JA, Xiang Z, O'Neal J, Kreisel F, Colson A, Luo H, Hennighausen L, Tomasson MH. Cain JA, et al. Among authors: hennighausen l. Blood. 2007 May 1;109(9):3906-14. doi: 10.1182/blood-2006-07-036335. Epub 2007 Jan 11. Blood. 2007. PMID: 17218386 Free PMC article.

5

Direct glucocorticoid receptor-Stat5 interaction in hepatocytes controls body size and maturation-related gene expression.

Engblom D, Kornfeld JW, Schwake L, Tronche F, Reimann A, Beug H, Hennighausen L, Moriggl R, Schütz G. Engblom D, et al. Among authors: hennighausen l. Genes Dev. 2007 May 15;21(10):1157-62. doi: 10.1101/gad.426007. Genes Dev. 2007. PMID: 17504935 Free PMC article.

6

Csf3r mutations in mice confer a strong clonal HSC advantage via activation of Stat5.

Liu F, Kunter G, Krem MM, Eades WC, Cain JA, Tomasson MH, Hennighausen L, Link DC. Liu F, et al. Among authors: hennighausen l. J Clin Invest. 2008 Mar;118(3):946-55. doi: 10.1172/JCI32704. J Clin Invest. 2008. PMID: 18292815 Free PMC article.

7

STAT5-regulated microRNA-193b controls haematopoietic stem and progenitor cell expansion by modulating cytokine receptor signalling.

Haetscher N, Feuermann Y, Wingert S, Rehage M, Thalheimer FB, Weiser C, Bohnenberger H, Jung K, Schroeder T, Serve H, Oellerich T, Hennighausen L, Rieger MA. Haetscher N, et al. Among authors: hennighausen l. Nat Commun. 2015 Nov 25;6:8928. doi: 10.1038/ncomms9928. Nat Commun. 2015. PMID: 26603207 Free PMC article.

8

Facultative CTCF sites moderate mammary super-enhancer activity and regulate juxtaposed gene in non-mammary cells.

Willi M, Yoo KH, Reinisch F, Kuhns TM, Lee HK, Wang C, Hennighausen L. Willi M, et al. Among authors: hennighausen l. Nat Commun. 2017 Jul 17;8:16069. doi: 10.1038/ncomms16069. Nat Commun. 2017. PMID: 28714474 Free PMC article.

9

STAT5 is crucial to maintain leukemic stem cells in acute myelogenous leukemias induced by MOZ-TIF2.

Tam WF, Hähnel PS, Schüler A, Lee BH, Okabe R, Zhu N, Pante SV, Raffel G, Mercher T, Wernig G, Bockamp E, Sasca D, Kreft A, Robinson GW, Hennighausen L, Gilliland DG, Kindler T. Tam WF, et al. Among authors: hennighausen l. Cancer Res. 2013 Jan 1;73(1):373-84. doi: 10.1158/0008-5472.CAN-12-0255. Epub 2012 Nov 13. Cancer Res. 2013. PMID: 23149921 Free PMC article.

10

Cytokine-regulated GADD45G induces differentiation and lineage selection in hematopoietic stem cells.

Thalheimer FB, Wingert S, De Giacomo P, Haetscher N, Rehage M, Brill B, Theis FJ, Hennighausen L, Schroeder T, Rieger MA. Thalheimer FB, et al. Among authors: hennighausen l. Stem Cell Reports. 2014 Jun 19;3(1):34-43. doi: 10.1016/j.stemcr.2014.05.010. eCollection 2014 Jul 8. Stem Cell Reports. 2014. PMID: 25068120 Free PMC article.

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