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39 results

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Page 1
Inhibition of hematopoietic protein tyrosine phosphatase augments and prolongs ERK1/2 and p38 activation.
Sergienko E, Xu J, Liu WH, Dahl R, Critton DA, Su Y, Brown BT, Chan X, Yang L, Bobkova EV, Vasile S, Yuan H, Rascon J, Colayco S, Sidique S, Cosford ND, Chung TD, Mustelin T, Page R, Lombroso PJ, Tautz L. Sergienko E, et al. Among authors: bobkova ev. ACS Chem Biol. 2012 Feb 17;7(2):367-77. doi: 10.1021/cb2004274. Epub 2011 Nov 17. ACS Chem Biol. 2012. PMID: 22070201 Free PMC article.
Identification of a selective inhibitor of murine intestinal alkaline phosphatase (ML260) by concurrent ultra-high throughput screening against human and mouse isozymes.
Ardecky RJ, Bobkova EV, Kiffer-Moreira T, Brown B, Ganji S, Zou J, Pass I, Narisawa S, Iano FG, Rosenstein C, Cheltsov A, Rascon J, Hedrick M, Gasior C, Forster A, Shi S, Dahl R, Vasile S, Su Y, Sergienko E, Chung TDY, Kaunitz J, Hoylaerts MF, Pinkerton AB, Millán JL. Ardecky RJ, et al. Among authors: bobkova ev. Bioorg Med Chem Lett. 2014 Feb 1;24(3):1000-1004. doi: 10.1016/j.bmcl.2013.12.043. Epub 2013 Dec 19. Bioorg Med Chem Lett. 2014. PMID: 24412070 Free PMC article.
Modulators of intestinal alkaline phosphatase.
Bobkova EV, Kiffer-Moreira T, Sergienko EA. Bobkova EV, et al. Methods Mol Biol. 2013;1053:135-44. doi: 10.1007/978-1-62703-562-0_9. Methods Mol Biol. 2013. PMID: 23860652
Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.
Musumeci L, Kuijpers MJ, Gilio K, Hego A, Théâtre E, Maurissen L, Vandereyken M, Diogo CV, Lecut C, Guilmain W, Bobkova EV, Eble JA, Dahl R, Drion P, Rascon J, Mostofi Y, Yuan H, Sergienko E, Chung TD, Thiry M, Senis Y, Moutschen M, Mustelin T, Lancellotti P, Heemskerk JW, Tautz L, Oury C, Rahmouni S. Musumeci L, et al. Among authors: bobkova ev. Circulation. 2015 Feb 17;131(7):656-68. doi: 10.1161/CIRCULATIONAHA.114.010186. Epub 2014 Dec 17. Circulation. 2015. PMID: 25520375 Free PMC article.
Allosteric Inhibition of Ubiquitin-like Modifications by a Class of Inhibitor of SUMO-Activating Enzyme.
Li YJ, Du L, Wang J, Vega R, Lee TD, Miao Y, Aldana-Masangkay G, Samuels ER, Li B, Ouyang SX, Colayco SA, Bobkova EV, Divlianska DB, Sergienko E, Chung TDY, Fakih M, Chen Y. Li YJ, et al. Among authors: bobkova ev. Cell Chem Biol. 2019 Feb 21;26(2):278-288.e6. doi: 10.1016/j.chembiol.2018.10.026. Epub 2018 Dec 20. Cell Chem Biol. 2019. PMID: 30581133 Free PMC article.
A scintillation proximity assay for rna detection.
Liu J, Feldman PA, Lippy JS, Bobkova E, Kurilla MG, Chung TD. Liu J, et al. Anal Biochem. 2001 Feb 15;289(2):239-45. doi: 10.1006/abio.2000.4944. Anal Biochem. 2001. PMID: 11161317
Biochemical analysis of protein SUMOylation.
Alontaga AY, Bobkova E, Chen Y. Alontaga AY, et al. Curr Protoc Mol Biol. 2012 Jul;Chapter 10:Unit10.29. doi: 10.1002/0471142727.mb1029s99. Curr Protoc Mol Biol. 2012. PMID: 22870855 Free PMC article.
Identification of direct target engagement biomarkers for kinase-targeted therapeutics.
Paweletz CP, Andersen JN, Pollock R, Nagashima K, Hayashi ML, Yu SU, Guo H, Bobkova EV, Xu Z, Northrup A, Blume-Jensen P, Hendrickson RC, Chi A. Paweletz CP, et al. Among authors: bobkova ev. PLoS One. 2011;6(10):e26459. doi: 10.1371/journal.pone.0026459. Epub 2011 Oct 24. PLoS One. 2011. PMID: 22039492 Free PMC article.
39 results