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Trafficking and gating of hyperpolarization-activated cyclic nucleotide-gated channels are regulated by interaction with tetratricopeptide repeat-containing Rab8b-interacting protein (TRIP8b) and cyclic AMP at distinct sites.
Han Y, Noam Y, Lewis AS, Gallagher JJ, Wadman WJ, Baram TZ, Chetkovich DM. Han Y, et al. Among authors: lewis as. J Biol Chem. 2011 Jun 10;286(23):20823-34. doi: 10.1074/jbc.M111.236125. Epub 2011 Apr 19. J Biol Chem. 2011. PMID: 21504900 Free PMC article.
Deletion of the hyperpolarization-activated cyclic nucleotide-gated channel auxiliary subunit TRIP8b impairs hippocampal Ih localization and function and promotes antidepressant behavior in mice.
Lewis AS, Vaidya SP, Blaiss CA, Liu Z, Stoub TR, Brager DH, Chen X, Bender RA, Estep CM, Popov AB, Kang CE, Van Veldhoven PP, Bayliss DA, Nicholson DA, Powell CM, Johnston D, Chetkovich DM. Lewis AS, et al. J Neurosci. 2011 May 18;31(20):7424-40. doi: 10.1523/JNEUROSCI.0936-11.2011. J Neurosci. 2011. PMID: 21593326 Free PMC article.
Differential dorso-ventral distributions of Kv4.2 and HCN proteins confer distinct integrative properties to hippocampal CA1 pyramidal cell distal dendrites.
Marcelin B, Lugo JN, Brewster AL, Liu Z, Lewis AS, McClelland S, Chetkovich DM, Baram TZ, Anderson AE, Becker A, Esclapez M, Bernard C. Marcelin B, et al. Among authors: lewis as. J Biol Chem. 2012 May 18;287(21):17656-17661. doi: 10.1074/jbc.C112.367110. Epub 2012 Apr 16. J Biol Chem. 2012. PMID: 22511771 Free PMC article.
HCN channelopathy in external globus pallidus neurons in models of Parkinson's disease.
Chan CS, Glajch KE, Gertler TS, Guzman JN, Mercer JN, Lewis AS, Goldberg AB, Tkatch T, Shigemoto R, Fleming SM, Chetkovich DM, Osten P, Kita H, Surmeier DJ. Chan CS, et al. Among authors: lewis as. Nat Neurosci. 2011 Jan;14(1):85-92. doi: 10.1038/nn.2692. Epub 2010 Nov 14. Nat Neurosci. 2011. PMID: 21076425 Free PMC article.
100 results