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Page 1
'Less is More': defining modern bioanalysis.
Dijksman J, Timmerman P, Abbott R, Barroso B, Kloeppel MB, Companjen A, Golob M, Gordon B, Herling C, Knutsson M, Luedtke S, Rasmussen BB, Stoellner D, Vieser E, Young G, van Amsterdam P. Dijksman J, et al. Among authors: vieser e. Bioanalysis. 2012 Mar;4(6):633-42. doi: 10.4155/bio.12.36. Bioanalysis. 2012. PMID: 22452252
A multicenter phase 1 study of solitomab (MT110, AMG 110), a bispecific EpCAM/CD3 T-cell engager (BiTE®) antibody construct, in patients with refractory solid tumors.
Kebenko M, Goebeler ME, Wolf M, Hasenburg A, Seggewiss-Bernhardt R, Ritter B, Rautenberg B, Atanackovic D, Kratzer A, Rottman JB, Friedrich M, Vieser E, Elm S, Patzak I, Wessiepe D, Stienen S, Fiedler W. Kebenko M, et al. Among authors: vieser e. Oncoimmunology. 2018 Apr 18;7(8):e1450710. doi: 10.1080/2162402X.2018.1450710. eCollection 2018. Oncoimmunology. 2018. PMID: 30221040 Free PMC article.
The interleukin-2 antagonizing antibody MT204 delays allogeneic skin graft rejection in non-human primates and is well tolerated.
Plater-Zyberk C, Lopes Estêvão DM, d'Argouges S, Haanstra KG, Kondova I, Vierboom M, Boehm T, Neef R, Vieser EM, Rattel B, Baeuerle PA, Jonker M. Plater-Zyberk C, et al. Among authors: vieser em. Transpl Immunol. 2011 Sep;25(2-3):133-40. doi: 10.1016/j.trim.2011.06.003. Epub 2011 Jun 25. Transpl Immunol. 2011. PMID: 21708251
Therapeutic window of an EpCAM/CD3-specific BiTE antibody in mice is determined by a subpopulation of EpCAM-expressing lymphocytes that is absent in humans.
Amann M, Friedrich M, Lutterbuese P, Vieser E, Lorenczewski G, Petersen L, Brischwein K, Kufer P, Kischel R, Baeuerle PA, Schlereth B. Amann M, et al. Among authors: vieser e. Cancer Immunol Immunother. 2009 Jan;58(1):95-109. doi: 10.1007/s00262-008-0529-y. Epub 2008 Jul 2. Cancer Immunol Immunother. 2009. PMID: 18594818 Free PMC article.