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Stopping randomized trials early for benefit: a protocol of the Study Of Trial Policy Of Interim Truncation-2 (STOPIT-2).
Briel M, Lane M, Montori VM, Bassler D, Glasziou P, Malaga G, Akl EA, Ferreira-Gonzalez I, Alonso-Coello P, Urrutia G, Kunz R, Culebro CR, da Silva SA, Flynn DN, Elamin MB, Strahm B, Murad MH, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Abu Elnour NO, You JJ, Karanicolas PJ, Bucher HC, Lampropulos JF, Nordmann AJ, Burns KE, Mulla SM, Raatz H, Sood A, Kaur J, Bankhead CR, Mullan RJ, Nerenberg KA, Vandvik PO, Coto-Yglesias F, Schünemann H, Tuche F, Chrispim PP, Cook DJ, Lutz K, Ribic CM, Vale N, Erwin PJ, Perera R, Zhou Q, Heels-Ansdell D, Ramsay T, Walter SD, Guyatt GH. Briel M, et al. Among authors: akl ea. Trials. 2009 Jul 6;10:49. doi: 10.1186/1745-6215-10-49. Trials. 2009. PMID: 19580665 Free PMC article.
Subgroup Analysis of Trials Is Rarely Easy (SATIRE): a study protocol for a systematic review to characterize the analysis, reporting, and claim of subgroup effects in randomized trials.
Sun X, Briel M, Busse JW, Akl EA, You JJ, Mejza F, Bala M, Diaz-Granados N, Bassler D, Mertz D, Srinathan SK, Vandvik PO, Malaga G, Alshurafa M, Dahm P, Alonso-Coello P, Heels-Ansdell DM, Bhatnagar N, Johnston BC, Wang L, Walter SD, Altman DG, Guyatt GH. Sun X, et al. Among authors: akl ea. Trials. 2009 Nov 9;10:101. doi: 10.1186/1745-6215-10-101. Trials. 2009. PMID: 19900273 Free PMC article.
Stopping randomized trials early for benefit and estimation of treatment effects: systematic review and meta-regression analysis.
Bassler D, Briel M, Montori VM, Lane M, Glasziou P, Zhou Q, Heels-Ansdell D, Walter SD, Guyatt GH; STOPIT-2 Study Group; Flynn DN, Elamin MB, Murad MH, Abu Elnour NO, Lampropulos JF, Sood A, Mullan RJ, Erwin PJ, Bankhead CR, Perera R, Ruiz Culebro C, You JJ, Mulla SM, Kaur J, Nerenberg KA, Schünemann H, Cook DJ, Lutz K, Ribic CM, Vale N, Malaga G, Akl EA, Ferreira-Gonzalez I, Alonso-Coello P, Urrutia G, Kunz R, Bucher HC, Nordmann AJ, Raatz H, da Silva SA, Tuche F, Strahm B, Djulbegovic B, Adhikari NK, Mills EJ, Gwadry-Sridhar F, Kirpalani H, Soares HP, Karanicolas PJ, Burns KE, Vandvik PO, Coto-Yglesias F, Chrispim PP, Ramsay T. Bassler D, et al. Among authors: akl ea. JAMA. 2010 Mar 24;303(12):1180-7. doi: 10.1001/jama.2010.310. JAMA. 2010. PMID: 20332404 Review.
The influence of study characteristics on reporting of subgroup analyses in randomised controlled trials: systematic review.
Sun X, Briel M, Busse JW, You JJ, Akl EA, Mejza F, Bala MM, Bassler D, Mertz D, Diaz-Granados N, Vandvik PO, Malaga G, Srinathan SK, Dahm P, Johnston BC, Alonso-Coello P, Hassouneh B, Truong J, Dattani ND, Walter SD, Heels-Ansdell D, Bhatnagar N, Altman DG, Guyatt GH. Sun X, et al. Among authors: akl ea. BMJ. 2011 Mar 28;342:d1569. doi: 10.1136/bmj.d1569. BMJ. 2011. PMID: 21444636 Free PMC article. Review.
Completion and Publication Rates of Randomized Controlled Trials in Surgery: An Empirical Study.
Rosenthal R, Kasenda B, Dell-Kuster S, von Elm E, You J, Blümle A, Tomonaga Y, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla S, Mertz D, Akl EA, Bassler D, Busse JW, Ferreira-González I, Lamontagne F, Nordmann A, Gloy V, Olu KK, Raatz H, Moja L, Ebrahim S, Schandelmaier S, Sun X, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Bucher HC, Guyatt GH, Briel M. Rosenthal R, et al. Among authors: akl ea. Ann Surg. 2015 Jul;262(1):68-73. doi: 10.1097/SLA.0000000000000810. Ann Surg. 2015. PMID: 24979608 Free article.
Premature Discontinuation of Randomized Trials in Critical and Emergency Care: A Retrospective Cohort Study.
Schandelmaier S, von Elm E, You JJ, Blümle A, Tomonaga Y, Lamontagne F, Saccilotto R, Amstutz A, Bengough T, Meerpohl JJ, Stegert M, Olu KK, Tikkinen KA, Neumann I, Carrasco-Labra A, Faulhaber M, Mulla SM, Mertz D, Akl EA, Sun X, Bassler D, Busse JW, Ferreira-González I, Nordmann A, Gloy V, Raatz H, Moja L, Rosenthal R, Ebrahim S, Vandvik PO, Johnston BC, Walter MA, Burnand B, Schwenkglenks M, Hemkens LG, Cook DJ, Meade MO, Bucher HC, Kasenda B, Briel M. Schandelmaier S, et al. Among authors: akl ea. Crit Care Med. 2016 Jan;44(1):130-7. doi: 10.1097/CCM.0000000000001369. Crit Care Med. 2016. PMID: 26468895 Free article.
Sensitivity subgroup analysis based on single-center vs. multi-center trial status when interpreting meta-analyses pooled estimates: the logical way forward.
Alexander PE, Bonner AJ, Agarwal A, Li SA, Hariharan A 4th, Izhar Z, Bhatnagar N, Alba C, Akl EA, Fei Y, Guyatt GH, Beyene J. Alexander PE, et al. Among authors: akl ea. J Clin Epidemiol. 2016 Jun;74:80-92. doi: 10.1016/j.jclinepi.2015.08.027. Epub 2015 Nov 17. J Clin Epidemiol. 2016. PMID: 26597972 Review.
Randomized trials addressing a similar question are commonly published after a trial stopped early for benefit.
Murad MH, Guyatt GH, Domecq JP, Vernooij RWM, Erwin PJ, Meerpohl JJ, Prutsky GJ, Akl EA, Mueller K, Bassler D, Schandelmaier S, Walter SD, Busse JW, Kasenda B, Pagano G, Pardo-Hernandez H, Montori VM, Wang Z, Briel M. Murad MH, et al. Among authors: akl ea. J Clin Epidemiol. 2017 Feb;82:12-19. doi: 10.1016/j.jclinepi.2016.10.006. Epub 2016 Nov 8. J Clin Epidemiol. 2017. PMID: 27832953 Free article. Review.
556 results