Piloto O - Search Results

1

Further activation of FLT3 mutants by FLT3 ligand.

Zheng R, Bailey E, Nguyen B, Yang X, Piloto O, Levis M, Small D. Zheng R, et al. Among authors: piloto o. Oncogene. 2011 Sep 22;30(38):4004-14. doi: 10.1038/onc.2011.110. Epub 2011 Apr 25. Oncogene. 2011. PMID: 21516120 Free PMC article.

2

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells.

Zheng R, Levis M, Piloto O, Brown P, Baldwin BR, Gorin NC, Beran M, Zhu Z, Ludwig D, Hicklin D, Witte L, Li Y, Small D. Zheng R, et al. Among authors: piloto o. Blood. 2004 Jan 1;103(1):267-74. doi: 10.1182/blood-2003-06-1969. Epub 2003 Sep 11. Blood. 2004. PMID: 12969963 Free article.

3

Inhibitory anti-FLT3 antibodies are capable of mediating antibody-dependent cell-mediated cytotoxicity and reducing engraftment of acute myelogenous leukemia blasts in nonobese diabetic/severe combined immunodeficient mice.

Piloto O, Levis M, Huso D, Li Y, Li H, Wang MN, Bassi R, Balderes P, Ludwig DL, Witte L, Zhu Z, Hicklin DJ, Small D. Piloto O, et al. Cancer Res. 2005 Feb 15;65(4):1514-22. doi: 10.1158/0008-5472.CAN-04-3081. Cancer Res. 2005. PMID: 15735040

4

IMC-EB10, an anti-FLT3 monoclonal antibody, prolongs survival and reduces nonobese diabetic/severe combined immunodeficient engraftment of some acute lymphoblastic leukemia cell lines and primary leukemic samples.

Piloto O, Nguyen B, Huso D, Kim KT, Li Y, Witte L, Hicklin DJ, Brown P, Small D. Piloto O, et al. Cancer Res. 2006 May 1;66(9):4843-51. doi: 10.1158/0008-5472.CAN-06-0018. Cancer Res. 2006. PMID: 16651440

5

Prolonged exposure to FLT3 inhibitors leads to resistance via activation of parallel signaling pathways.

Piloto O, Wright M, Brown P, Kim KT, Levis M, Small D. Piloto O, et al. Blood. 2007 Feb 15;109(4):1643-52. doi: 10.1182/blood-2006-05-023804. Epub 2006 Oct 17. Blood. 2007. PMID: 17047150 Free PMC article.

6

FLT3/ITD expression increases expansion, survival and entry into cell cycle of human haematopoietic stem/progenitor cells.

Li L, Piloto O, Kim KT, Ye Z, Nguyen HB, Yu X, Levis M, Cheng L, Small D. Li L, et al. Among authors: piloto o. Br J Haematol. 2007 Apr;137(1):64-75. doi: 10.1111/j.1365-2141.2007.06525.x. Br J Haematol. 2007. PMID: 17359372 Free article.

7

Constitutive Fms-like tyrosine kinase 3 activation results in specific changes in gene expression in myeloid leukaemic cells.

Kim KT, Baird K, Davis S, Piloto O, Levis M, Li L, Chen P, Meltzer P, Small D. Kim KT, et al. Among authors: piloto o. Br J Haematol. 2007 Sep;138(5):603-15. doi: 10.1111/j.1365-2141.2007.06696.x. Br J Haematol. 2007. PMID: 17686054 Free article.

8

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model.

Li L, Piloto O, Nguyen HB, Greenberg K, Takamiya K, Racke F, Huso D, Small D. Li L, et al. Among authors: piloto o. Blood. 2008 Apr 1;111(7):3849-58. doi: 10.1182/blood-2007-08-109942. Epub 2008 Feb 1. Blood. 2008. PMID: 18245664 Free PMC article.

9

Suppression of leukemia expressing wild-type or ITD-mutant FLT3 receptor by a fully human anti-FLT3 neutralizing antibody.

Li Y, Li H, Wang MN, Lu D, Bassi R, Wu Y, Zhang H, Balderes P, Ludwig DL, Pytowski B, Kussie P, Piloto O, Small D, Bohlen P, Witte L, Zhu Z, Hicklin DJ. Li Y, et al. Among authors: piloto o. Blood. 2004 Aug 15;104(4):1137-44. doi: 10.1182/blood-2003-07-2585. Epub 2004 Apr 22. Blood. 2004. PMID: 15105287 Free article.

10

Glycogen synthase kinase 3 in MLL leukaemia maintenance and targeted therapy.

Wang Z, Smith KS, Murphy M, Piloto O, Somervaille TC, Cleary ML. Wang Z, et al. Among authors: piloto o. Nature. 2008 Oct 30;455(7217):1205-9. doi: 10.1038/nature07284. Epub 2008 Sep 17. Nature. 2008. PMID: 18806775 Free PMC article.

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