Zheng R - Search Results

1

Further activation of FLT3 mutants by FLT3 ligand.

Zheng R, Bailey E, Nguyen B, Yang X, Piloto O, Levis M, Small D. Zheng R, et al. Oncogene. 2011 Sep 22;30(38):4004-14. doi: 10.1038/onc.2011.110. Epub 2011 Apr 25. Oncogene. 2011. PMID: 21516120 Free PMC article.

2

A FLT3-targeted tyrosine kinase inhibitor is cytotoxic to leukemia cells in vitro and in vivo.

Levis M, Allebach J, Tse KF, Zheng R, Baldwin BR, Smith BD, Jones-Bolin S, Ruggeri B, Dionne C, Small D. Levis M, et al. Among authors: zheng r. Blood. 2002 Jun 1;99(11):3885-91. doi: 10.1182/blood.v99.11.3885. Blood. 2002. PMID: 12010785 Free article.

3

Targeted inhibition of FLT3 overcomes the block to myeloid differentiation in 32Dcl3 cells caused by expression of FLT3/ITD mutations.

Zheng R, Friedman AD, Small D. Zheng R, et al. Blood. 2002 Dec 1;100(12):4154-61. doi: 10.1182/blood-2002-03-0936. Epub 2002 Aug 1. Blood. 2002. PMID: 12393674 Free article.

4

FLT3 ligand causes autocrine signaling in acute myeloid leukemia cells.

Zheng R, Levis M, Piloto O, Brown P, Baldwin BR, Gorin NC, Beran M, Zhu Z, Ludwig D, Hicklin D, Witte L, Li Y, Small D. Zheng R, et al. Blood. 2004 Jan 1;103(1):267-74. doi: 10.1182/blood-2003-06-1969. Epub 2003 Sep 11. Blood. 2004. PMID: 12969963 Free article.

5

Internal tandem duplication mutation of FLT3 blocks myeloid differentiation through suppression of C/EBPalpha expression.

Zheng R, Friedman AD, Levis M, Li L, Weir EG, Small D. Zheng R, et al. Blood. 2004 Mar 1;103(5):1883-90. doi: 10.1182/blood-2003-06-1978. Epub 2003 Oct 30. Blood. 2004. PMID: 14592841 Free article.

6

Mutant FLT3 signaling contributes to a block in myeloid differentiation.

Zheng R, Small D. Zheng R, et al. Leuk Lymphoma. 2005 Dec;46(12):1679-87. doi: 10.1080/10428190500261740. Leuk Lymphoma. 2005. PMID: 16263569 Review.

7

Lack of KIT or FMS internal tandem duplications but co-expression with ligands in AML.

Zheng R, Klang K, Gorin NC, Small D. Zheng R, et al. Leuk Res. 2004 Feb;28(2):121-6. doi: 10.1016/s0145-2126(03)00184-x. Leuk Res. 2004. PMID: 14654075

8

Human AML cells in NOD/SCID mice: engraftment potential and gene expression.

Lumkul R, Gorin NC, Malehorn MT, Hoehn GT, Zheng R, Baldwin B, Small D, Gore S, Smith D, Meltzer PS, Civin CI. Lumkul R, et al. Among authors: zheng r. Leukemia. 2002 Sep;16(9):1818-26. doi: 10.1038/sj.leu.2402632. Leukemia. 2002. PMID: 12200698

9

Block of C/EBP alpha function by phosphorylation in acute myeloid leukemia with FLT3 activating mutations.

Radomska HS, Bassères DS, Zheng R, Zhang P, Dayaram T, Yamamoto Y, Sternberg DW, Lokker N, Giese NA, Bohlander SK, Schnittger S, Delmotte MH, Davis RJ, Small D, Hiddemann W, Gilliland DG, Tenen DG. Radomska HS, et al. Among authors: zheng r. J Exp Med. 2006 Feb 20;203(2):371-81. doi: 10.1084/jem.20052242. Epub 2006 Jan 30. J Exp Med. 2006. PMID: 16446383 Free PMC article.

10

A leukemic presentation of alveolar rhabdomyosarcoma in a 52-year-old woman without an identifiable primary tumor.

Kern JB, Hii A, Kruse MJ, Szabo Z, Argani P, Hibbard MK, Gladstone DE, Meyer C, Zheng R, Borowitz MJ, Duffield AS. Kern JB, et al. Among authors: zheng r. Int J Surg Pathol. 2015 Feb;23(1):75-7. doi: 10.1177/1066896914553666. Epub 2014 Oct 10. Int J Surg Pathol. 2015. PMID: 25305220 Free PMC article.

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