Felczak K - Search Results

1

Rehab of NAD(P)-dependent enzymes with NAD(P)-based inhibitors.

Felczak K, Pankiewicz KW. Felczak K, et al. Curr Med Chem. 2011;18(13):1891-908. doi: 10.2174/092986711795590066. Curr Med Chem. 2011. PMID: 21517781 Review.

2

Nicotinamide adenine dinucleotide based therapeutics.

Chen L, Petrelli R, Felczak K, Gao G, Bonnac L, Yu JS, Bennett EM, Pankiewicz KW. Chen L, et al. Among authors: felczak k. Curr Med Chem. 2008;15(7):650-70. doi: 10.2174/092986708783885282. Curr Med Chem. 2008. PMID: 18336280 Review.

3

Nicotinamide Adenine Dinucleotide Based Therapeutics, Update.

Pankiewicz KW, Petrelli R, Singh R, Felczak K. Pankiewicz KW, et al. Among authors: felczak k. Curr Med Chem. 2015;22(34):3991-4028. doi: 10.2174/0929867322666150821100720. Curr Med Chem. 2015. PMID: 26295463 Review.

4

Probing binding requirements of NAD kinase with modified substrate (NAD) analogues.

Bonnac L, Chen L, Pathak R, Gao G, Ming Q, Bennett E, Felczak K, Kullberg M, Patterson SE, Mazzola F, Magni G, Pankiewicz KW. Bonnac L, et al. Among authors: felczak k. Bioorg Med Chem Lett. 2007 Mar 15;17(6):1512-5. doi: 10.1016/j.bmcl.2007.01.012. Epub 2007 Jan 17. Bioorg Med Chem Lett. 2007. PMID: 17258457

5

Synthesis of 4-phenoxybenzamide adenine dinucleotide as NAD analogue with inhibitory activity against enoyl-ACP reductase (InhA) of Mycobacterium tuberculosis.

Bonnac L, Gao GY, Chen L, Felczak K, Bennett EM, Xu H, Kim T, Liu N, Oh H, Tonge PJ, Pankiewicz KW. Bonnac L, et al. Among authors: felczak k. Bioorg Med Chem Lett. 2007 Aug 15;17(16):4588-91. doi: 10.1016/j.bmcl.2007.05.084. Epub 2007 May 31. Bioorg Med Chem Lett. 2007. PMID: 17560106

6

Probing binding requirements of type I and type II isoforms of inosine monophosphate dehydrogenase with adenine-modified nicotinamide adenine dinucleotide analogues.

Chen L, Gao G, Felczak K, Bonnac L, Patterson SE, Wilson D, Bennett EM, Jayaram HN, Hedstrom L, Pankiewicz KW. Chen L, et al. Among authors: felczak k. J Med Chem. 2007 Nov 15;50(23):5743-51. doi: 10.1021/jm070568j. Epub 2007 Oct 24. J Med Chem. 2007. PMID: 17958343

7

Selective inhibition of nicotinamide adenine dinucleotide kinases by dinucleoside disulfide mimics of nicotinamide adenine dinucleotide analogues.

Petrelli R, Sham YY, Chen L, Felczak K, Bennett E, Wilson D, Aldrich C, Yu JS, Cappellacci L, Franchetti P, Grifantini M, Mazzola F, Di Stefano M, Magni G, Pankiewicz KW. Petrelli R, et al. Among authors: felczak k. Bioorg Med Chem. 2009 Aug 1;17(15):5656-64. doi: 10.1016/j.bmc.2009.06.013. Epub 2009 Jun 13. Bioorg Med Chem. 2009. PMID: 19596199

8

Triazole-linked inhibitors of inosine monophosphate dehydrogenase from human and Mycobacterium tuberculosis.

Chen L, Wilson DJ, Xu Y, Aldrich CC, Felczak K, Sham YY, Pankiewicz KW. Chen L, et al. Among authors: felczak k. J Med Chem. 2010 Jun 24;53(12):4768-78. doi: 10.1021/jm100424m. J Med Chem. 2010. PMID: 20491506 Free PMC article.

9

Cofactor-type inhibitors of inosine monophosphate dehydrogenase via modular approach: targeting the pyrophosphate binding sub-domain.

Felczak K, Chen L, Wilson D, Williams J, Vince R, Petrelli R, Jayaram HN, Kusumanchi P, Kumar M, Pankiewicz KW. Felczak K, et al. Bioorg Med Chem. 2011 Mar 1;19(5):1594-605. doi: 10.1016/j.bmc.2011.01.042. Epub 2011 Jan 27. Bioorg Med Chem. 2011. PMID: 21324702

10

NAD-based inhibitors with anticancer potential.

Felczak K, Vince R, Pankiewicz KW. Felczak K, et al. Bioorg Med Chem Lett. 2014 Jan 1;24(1):332-6. doi: 10.1016/j.bmcl.2013.11.005. Epub 2013 Nov 14. Bioorg Med Chem Lett. 2014. PMID: 24269162

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