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Neuronal Sirt1 deficiency increases insulin sensitivity in both brain and peripheral tissues.
Lu M, Sarruf DA, Li P, Osborn O, Sanchez-Alavez M, Talukdar S, Chen A, Bandyopadhyay G, Xu J, Morinaga H, Dines K, Watkins S, Kaiyala K, Schwartz MW, Olefsky JM. Lu M, et al. Among authors: sarruf da. J Biol Chem. 2013 Apr 12;288(15):10722-35. doi: 10.1074/jbc.M112.443606. Epub 2013 Mar 1. J Biol Chem. 2013. PMID: 23457303 Free PMC article.
New clues to bariatric surgery's benefits.
Sarruf DA, Bonner-Weir S, Schwartz MW. Sarruf DA, et al. Nat Med. 2012 Jun 6;18(6):860-1. doi: 10.1038/nm.2801. Nat Med. 2012. PMID: 22673995 Free PMC article.
Peroxisome proliferation-associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity.
Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett AM, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL. Diano S, et al. Among authors: sarruf da. Nat Med. 2011 Aug 28;17(9):1121-7. doi: 10.1038/nm.2421. Nat Med. 2011. PMID: 21873987 Free PMC article.
Leptin deficiency causes insulin resistance induced by uncontrolled diabetes.
German JP, Wisse BE, Thaler JP, Oh-I S, Sarruf DA, Ogimoto K, Kaiyala KJ, Fischer JD, Matsen ME, Taborsky GJ Jr, Schwartz MW, Morton GJ. German JP, et al. Among authors: sarruf da. Diabetes. 2010 Jul;59(7):1626-34. doi: 10.2337/db09-1918. Epub 2010 Apr 27. Diabetes. 2010. PMID: 20424233 Free PMC article.
Obesity is associated with hypothalamic injury in rodents and humans.
Thaler JP, Yi CX, Schur EA, Guyenet SJ, Hwang BH, Dietrich MO, Zhao X, Sarruf DA, Izgur V, Maravilla KR, Nguyen HT, Fischer JD, Matsen ME, Wisse BE, Morton GJ, Horvath TL, Baskin DG, Tschöp MH, Schwartz MW. Thaler JP, et al. Among authors: sarruf da. J Clin Invest. 2012 Jan;122(1):153-62. doi: 10.1172/JCI59660. Epub 2011 Dec 27. J Clin Invest. 2012. PMID: 22201683 Free PMC article.
14 results