Cheng JQ - Search Results

1

Combination of farnesyltransferase and Akt inhibitors is synergistic in breast cancer cells and causes significant breast tumor regression in ErbB2 transgenic mice.

Balasis ME, Forinash KD, Chen YA, Fulp WJ, Coppola D, Hamilton AD, Cheng JQ, Sebti SM. Balasis ME, et al. Among authors: cheng jq. Clin Cancer Res. 2011 May 1;17(9):2852-62. doi: 10.1158/1078-0432.CCR-10-2544. Clin Cancer Res. 2011. PMID: 21536547 Free PMC article.

2

AKT2, a member of the protein kinase B family, is activated by growth factors, v-Ha-ras, and v-src through phosphatidylinositol 3-kinase in human ovarian epithelial cancer cells.

Liu AX, Testa JR, Hamilton TC, Jove R, Nicosia SV, Cheng JQ. Liu AX, et al. Among authors: cheng jq. Cancer Res. 1998 Jul 15;58(14):2973-7. Cancer Res. 1998. PMID: 9679957

3

The phosphoinositide 3-OH kinase/AKT2 pathway as a critical target for farnesyltransferase inhibitor-induced apoptosis.

Jiang K, Coppola D, Crespo NC, Nicosia SV, Hamilton AD, Sebti SM, Cheng JQ. Jiang K, et al. Among authors: cheng jq. Mol Cell Biol. 2000 Jan;20(1):139-48. doi: 10.1128/MCB.20.1.139-148.2000. Mol Cell Biol. 2000. PMID: 10594016 Free PMC article.

4

The p16 status of tumor cell lines identifies small molecule inhibitors specific for cyclin-dependent kinase 4.

Kubo A, Nakagawa K, Varma RK, Conrad NK, Cheng JQ, Lee WC, Testa JR, Johnson BE, Kaye FJ, Kelley MJ. Kubo A, et al. Among authors: cheng jq. Clin Cancer Res. 1999 Dec;5(12):4279-86. Clin Cancer Res. 1999. PMID: 10632371

5

Frequent activation of AKT2 and induction of apoptosis by inhibition of phosphoinositide-3-OH kinase/Akt pathway in human ovarian cancer.

Yuan ZQ, Sun M, Feldman RI, Wang G, Ma X, Jiang C, Coppola D, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: cheng jq. Oncogene. 2000 May 4;19(19):2324-30. doi: 10.1038/sj.onc.1203598. Oncogene. 2000. PMID: 10822383

6

Phosphatidylinositol-3-OH Kinase (PI3K)/AKT2, activated in breast cancer, regulates and is induced by estrogen receptor alpha (ERalpha) via interaction between ERalpha and PI3K.

Sun M, Paciga JE, Feldman RI, Yuan Z, Coppola D, Lu YY, Shelley SA, Nicosia SV, Cheng JQ. Sun M, et al. Among authors: cheng jq. Cancer Res. 2001 Aug 15;61(16):5985-91. Cancer Res. 2001. PMID: 11507039

7

Inhibition of JNK by cellular stress- and tumor necrosis factor alpha-induced AKT2 through activation of the NF kappa B pathway in human epithelial Cells.

Yuan ZQ, Feldman RI, Sun M, Olashaw NE, Coppola D, Sussman GE, Shelley SA, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: cheng jq. J Biol Chem. 2002 Aug 16;277(33):29973-82. doi: 10.1074/jbc.M203636200. Epub 2002 Jun 4. J Biol Chem. 2002. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22849. doi: 10.1074/jbc.A116.203636 PMID: 12048203 Free article. Retracted.

8

Telomerase is regulated by c-Jun NH2-terminal kinase in ovarian surface epithelial cells.

Alfonso-De Matte MY, Yang H, Evans MS, Cheng JQ, Kruk PA. Alfonso-De Matte MY, et al. Among authors: cheng jq. Cancer Res. 2002 Aug 15;62(16):4575-8. Cancer Res. 2002. PMID: 12183409

9

Activation and overexpression of centrosome kinase BTAK/Aurora-A in human ovarian cancer.

Gritsko TM, Coppola D, Paciga JE, Yang L, Sun M, Shelley SA, Fiorica JV, Nicosia SV, Cheng JQ. Gritsko TM, et al. Among authors: cheng jq. Clin Cancer Res. 2003 Apr;9(4):1420-6. Clin Cancer Res. 2003. PMID: 12684414

10

AKT2 inhibition of cisplatin-induced JNK/p38 and Bax activation by phosphorylation of ASK1: implication of AKT2 in chemoresistance.

Yuan ZQ, Feldman RI, Sussman GE, Coppola D, Nicosia SV, Cheng JQ. Yuan ZQ, et al. Among authors: cheng jq. J Biol Chem. 2003 Jun 27;278(26):23432-40. doi: 10.1074/jbc.M302674200. Epub 2003 Apr 15. J Biol Chem. 2003. Retraction in: J Biol Chem. 2016 Oct 21;291(43):22847. doi: 10.1074/jbc.A116.302674 PMID: 12697749 Free article. Retracted.

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