Friedman AD - Search Results

1

AP-1 protein induction during monopoiesis favors C/EBP: AP-1 heterodimers over C/EBP homodimerization and stimulates FosB transcription.

Hong S, Skaist AM, Wheelan SJ, Friedman AD. Hong S, et al. Among authors: friedman ad. J Leukoc Biol. 2011 Oct;90(4):643-51. doi: 10.1189/jlb.0111043. Epub 2011 May 4. J Leukoc Biol. 2011. PMID: 21543584 Free PMC article.

2

Granulopoiesis requires increased C/EBPα compared to monopoiesis, correlated with elevated Cebpa in immature G-CSF receptor versus M-CSF receptor expressing cells.

Ma O, Hong S, Guo H, Ghiaur G, Friedman AD. Ma O, et al. Among authors: friedman ad. PLoS One. 2014 Apr 21;9(4):e95784. doi: 10.1371/journal.pone.0095784. eCollection 2014. PLoS One. 2014. PMID: 24752325 Free PMC article.

3

The Cebpa +37-kb enhancer directs transgene expression to myeloid progenitors and to long-term hematopoietic stem cells.

Guo H, Ma O, Friedman AD. Guo H, et al. Among authors: friedman ad. J Leukoc Biol. 2014 Sep;96(3):419-26. doi: 10.1189/jlb.2AB0314-145R. Epub 2014 May 27. J Leukoc Biol. 2014. PMID: 24868087 Free PMC article.

4

Cross-talk between regulators of myeloid development: C/EBPalpha binds and activates the promoter of the PU.1 gene.

Kummalue T, Friedman AD. Kummalue T, et al. Among authors: friedman ad. J Leukoc Biol. 2003 Sep;74(3):464-70. doi: 10.1189/jlb.1202622. J Leukoc Biol. 2003. PMID: 12949251

5

Runx1 deletion or dominant inhibition reduces Cebpa transcription via conserved promoter and distal enhancer sites to favor monopoiesis over granulopoiesis.

Guo H, Ma O, Speck NA, Friedman AD. Guo H, et al. Among authors: friedman ad. Blood. 2012 May 10;119(19):4408-18. doi: 10.1182/blood-2011-12-397091. Epub 2012 Mar 26. Blood. 2012. PMID: 22451420 Free PMC article.

6

C/EBP alpha:AP-1 leucine zipper heterodimers bind novel DNA elements, activate the PU.1 promoter and direct monocyte lineage commitment more potently than C/EBP alpha homodimers or AP-1.

Cai DH, Wang D, Keefer J, Yeamans C, Hensley K, Friedman AD. Cai DH, et al. Among authors: friedman ad. Oncogene. 2008 Apr 24;27(19):2772-9. doi: 10.1038/sj.onc.1210940. Epub 2007 Nov 19. Oncogene. 2008. PMID: 18026136 Free PMC article.

7

C/EBPα in normal and malignant myelopoiesis.

Friedman AD. Friedman AD. Int J Hematol. 2015 Apr;101(4):330-41. doi: 10.1007/s12185-015-1764-6. Epub 2015 Mar 10. Int J Hematol. 2015. PMID: 25753223 Free PMC article. Review.

8

C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction.

Dooher JE, Paz-Priel I, Houng S, Baldwin AS Jr, Friedman AD. Dooher JE, et al. Among authors: friedman ad. Mol Cancer Res. 2011 Oct;9(10):1395-405. doi: 10.1158/1541-7786.MCR-11-0072. Epub 2011 Aug 3. Mol Cancer Res. 2011. PMID: 21813505 Free PMC article.

9

C/EBPα dysregulation in AML and ALL.

Paz-Priel I, Friedman A. Paz-Priel I, et al. Crit Rev Oncog. 2011;16(1-2):93-102. doi: 10.1615/critrevoncog.v16.i1-2.90. Crit Rev Oncog. 2011. PMID: 22150310 Free PMC article. Review.

10

ZNF143 protein is an important regulator of the myeloid transcription factor C/EBPα.

Gonzalez D, Luyten A, Bartholdy B, Zhou Q, Kardosova M, Ebralidze A, Swanson KD, Radomska HS, Zhang P, Kobayashi SS, Welner RS, Levantini E, Steidl U, Chong G, Collombet S, Choi MH, Friedman AD, Scott LM, Alberich-Jorda M, Tenen DG. Gonzalez D, et al. Among authors: friedman ad. J Biol Chem. 2017 Nov 17;292(46):18924-18936. doi: 10.1074/jbc.M117.811109. Epub 2017 Sep 12. J Biol Chem. 2017. PMID: 28900037 Free PMC article.

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