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NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway.
Habbig S, Bartram MP, Müller RU, Schwarz R, Andriopoulos N, Chen S, Sägmüller JG, Hoehne M, Burst V, Liebau MC, Reinhardt HC, Benzing T, Schermer B. Habbig S, et al. Among authors: chen s. J Cell Biol. 2011 May 16;193(4):633-42. doi: 10.1083/jcb.201009069. Epub 2011 May 9. J Cell Biol. 2011. PMID: 21555462 Free PMC article.
Putting the brakes on p53-driven apoptosis.
Höpker K, Hagmann H, Khurshid S, Chen S, Schermer B, Benzing T, Reinhardt HC. Höpker K, et al. Among authors: chen s. Cell Cycle. 2012 Nov 15;11(22):4122-8. doi: 10.4161/cc.21997. Epub 2012 Sep 14. Cell Cycle. 2012. PMID: 22983126 Free PMC article.
AATF/Che-1 acts as a phosphorylation-dependent molecular modulator to repress p53-driven apoptosis.
Höpker K, Hagmann H, Khurshid S, Chen S, Hasskamp P, Seeger-Nukpezah T, Schilberg K, Heukamp L, Lamkemeyer T, Sos ML, Thomas RK, Lowery D, Roels F, Fischer M, Liebau MC, Resch U, Kisner T, Röther F, Bartram MP, Müller RU, Fabretti F, Kurschat P, Schumacher B, Gaestel M, Medema RH, Yaffe MB, Schermer B, Reinhardt HC, Benzing T. Höpker K, et al. Among authors: chen s. EMBO J. 2012 Oct 17;31(20):3961-75. doi: 10.1038/emboj.2012.236. Epub 2012 Aug 21. EMBO J. 2012. PMID: 22909821 Free PMC article.
[Synthetic lethality as a new concept for the treatment of cancer].
Herter-Sprie GS, Chen S, Höpker K, Reinhardt HC. Herter-Sprie GS, et al. Among authors: chen s. Dtsch Med Wochenschr. 2011 Jul;136(30):1526-30. doi: 10.1055/s-0031-1281549. Epub 2011 Jul 25. Dtsch Med Wochenschr. 2011. PMID: 21789751 Review. German.
Global transcriptome analysis of murine embryonic stem cell-derived cardiomyocytes.
Doss MX, Winkler J, Chen S, Hippler-Altenburg R, Sotiriadou I, Halbach M, Pfannkuche K, Liang H, Schulz H, Hummel O, Hübner N, Rottscheidt R, Hescheler J, Sachinidis A. Doss MX, et al. Among authors: chen s. Genome Biol. 2007;8(4):R56. doi: 10.1186/gb-2007-8-4-r56. Genome Biol. 2007. PMID: 17428332 Free PMC article.
Transcriptomic and phenotypic analysis of murine embryonic stem cell derived BMP2+ lineage cells: an insight into mesodermal patterning.
Doss MX, Chen S, Winkler J, Hippler-Altenburg R, Odenthal M, Wickenhauser C, Balaraman S, Schulz H, Hummel O, Hübner N, Ghosh-Choudhury N, Sotiriadou I, Hescheler J, Sachinidis A. Doss MX, et al. Among authors: chen s. Genome Biol. 2007;8(9):R184. doi: 10.1186/gb-2007-8-9-r184. Genome Biol. 2007. PMID: 17784959 Free PMC article.
Novel targets for ATM-deficient malignancies.
Winkler J, Hofmann K, Chen S. Winkler J, et al. Among authors: chen s. Mol Cell Oncol. 2014 Aug 13;1(1):e29905. doi: 10.4161/mco.29905. eCollection 2014. Mol Cell Oncol. 2014. PMID: 27308314 Free PMC article. Review.
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