Thurn KT - Search Results

1

A phase II study of the histone deacetylase inhibitor vorinostat combined with tamoxifen for the treatment of patients with hormone therapy-resistant breast cancer.

Munster PN, Thurn KT, Thomas S, Raha P, Lacevic M, Miller A, Melisko M, Ismail-Khan R, Rugo H, Moasser M, Minton SE. Munster PN, et al. Among authors: thurn kt. Br J Cancer. 2011 Jun 7;104(12):1828-35. doi: 10.1038/bjc.2011.156. Epub 2011 May 10. Br J Cancer. 2011. PMID: 21559012 Free PMC article. Clinical Trial.

2

Rational therapeutic combinations with histone deacetylase inhibitors for the treatment of cancer.

Thurn KT, Thomas S, Moore A, Munster PN. Thurn KT, et al. Future Oncol. 2011 Feb;7(2):263-83. doi: 10.2217/fon.11.2. Future Oncol. 2011. PMID: 21345145 Free PMC article. Review.

3

Efficacy of histone deacetylase and estrogen receptor inhibition in breast cancer cells due to concerted down regulation of Akt.

Thomas S, Thurn KT, Raha P, Chen S, Munster PN. Thomas S, et al. Among authors: thurn kt. PLoS One. 2013 Jul 9;8(7):e68973. doi: 10.1371/journal.pone.0068973. Print 2013. PLoS One. 2013. PMID: 23874830 Free PMC article.

4

Histone deacetylase regulation of ATM-mediated DNA damage signaling.

Thurn KT, Thomas S, Raha P, Qureshi I, Munster PN. Thurn KT, et al. Mol Cancer Ther. 2013 Oct;12(10):2078-87. doi: 10.1158/1535-7163.MCT-12-1242. Epub 2013 Aug 12. Mol Cancer Ther. 2013. PMID: 23939379 Free PMC article.

5

Addition of a histone deacetylase inhibitor redirects tamoxifen-treated breast cancer cells into apoptosis, which is opposed by the induction of autophagy.

Thomas S, Thurn KT, Biçaku E, Marchion DC, Münster PN. Thomas S, et al. Among authors: thurn kt. Breast Cancer Res Treat. 2011 Nov;130(2):437-47. doi: 10.1007/s10549-011-1364-y. Epub 2011 Feb 5. Breast Cancer Res Treat. 2011. PMID: 21298336 Free PMC article.

6

A phase I trial of panobinostat and epirubicin in solid tumors with a dose expansion in patients with sarcoma.

Thomas S, Aggarwal R, Jahan T, Ryan C, Troung T, Cripps AM, Raha P, Thurn KT, Chen S, Grabowsky JA, Park J, Hwang J, Daud A, Munster PN. Thomas S, et al. Among authors: thurn kt. Ann Oncol. 2016 May;27(5):947-52. doi: 10.1093/annonc/mdw044. Epub 2016 Feb 21. Ann Oncol. 2016. PMID: 26903311 Free PMC article. Clinical Trial.

7

Combined histone deacetylase inhibition and tamoxifen induces apoptosis in tamoxifen-resistant breast cancer models, by reversing Bcl-2 overexpression.

Raha P, Thomas S, Thurn KT, Park J, Munster PN. Raha P, et al. Among authors: thurn kt. Breast Cancer Res. 2015 Feb 25;17(1):26. doi: 10.1186/s13058-015-0533-z. Breast Cancer Res. 2015. PMID: 25848915 Free PMC article.

8

Endocytosis of titanium dioxide nanoparticles in prostate cancer PC-3M cells.

Thurn KT, Arora H, Paunesku T, Wu A, Brown EM, Doty C, Kremer J, Woloschak G. Thurn KT, et al. Nanomedicine. 2011 Apr;7(2):123-30. doi: 10.1016/j.nano.2010.09.004. Epub 2010 Sep 29. Nanomedicine. 2011. PMID: 20887814 Free PMC article.

9

Methods for assessing DNA hybridization of peptide nucleic acid-titanium dioxide nanoconjugates.

Brown EM, Paunesku T, Wu A, Thurn KT, Haley B, Clark J, Priester T, Woloschak GE. Brown EM, et al. Among authors: thurn kt. Anal Biochem. 2008 Dec 15;383(2):226-35. doi: 10.1016/j.ab.2008.08.020. Epub 2008 Aug 26. Anal Biochem. 2008. PMID: 18786502 Free PMC article.

10

Gadolinium-conjugated TiO2-DNA oligonucleotide nanoconjugates show prolonged intracellular retention period and T1-weighted contrast enhancement in magnetic resonance images.

Paunesku T, Ke T, Dharmakumar R, Mascheri N, Wu A, Lai B, Vogt S, Maser J, Thurn K, Szolc-Kowalska B, Larson A, Bergan RC, Omary R, Li D, Lu ZR, Woloschak GE. Paunesku T, et al. Nanomedicine. 2008 Sep;4(3):201-7. doi: 10.1016/j.nano.2008.04.004. Epub 2008 Jun 24. Nanomedicine. 2008. PMID: 18567541 Free PMC article.

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