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Next generation genome-wide association tool: design and coverage of a high-throughput European-optimized SNP array.
Hoffmann TJ, Kvale MN, Hesselson SE, Zhan Y, Aquino C, Cao Y, Cawley S, Chung E, Connell S, Eshragh J, Ewing M, Gollub J, Henderson M, Hubbell E, Iribarren C, Kaufman J, Lao RZ, Lu Y, Ludwig D, Mathauda GK, McGuire W, Mei G, Miles S, Purdy MM, Quesenberry C, Ranatunga D, Rowell S, Sadler M, Shapero MH, Shen L, Shenoy TR, Smethurst D, Van den Eeden SK, Walter L, Wan E, Wearley R, Webster T, Wen CC, Weng L, Whitmer RA, Williams A, Wong SC, Zau C, Finn A, Schaefer C, Kwok PY, Risch N. Hoffmann TJ, et al. Among authors: wen cc. Genomics. 2011 Aug;98(2):79-89. doi: 10.1016/j.ygeno.2011.04.005. Epub 2011 Apr 30. Genomics. 2011. PMID: 21565264 Free PMC article.
Functional characterization of liver enhancers that regulate drug-associated transporters.
Kim MJ, Skewes-Cox P, Fukushima H, Hesselson S, Yee SW, Ramsey LB, Nguyen L, Eshragh JL, Castro RA, Wen CC, Stryke D, Johns SJ, Ferrin TE, Kwok PY, Relling MV, Giacomini KM, Kroetz DL, Ahituv N. Kim MJ, et al. Among authors: wen cc. Clin Pharmacol Ther. 2011 Apr;89(4):571-8. doi: 10.1038/clpt.2010.353. Epub 2011 Mar 2. Clin Pharmacol Ther. 2011. PMID: 21368754 Free PMC article.
Genetic variants in transcription factors are associated with the pharmacokinetics and pharmacodynamics of metformin.
Goswami S, Yee SW, Stocker S, Mosley JD, Kubo M, Castro R, Mefford JA, Wen C, Liang X, Witte J, Brett C, Maeda S, Simpson MD, Hedderson MM, Davis RL, Roden DM, Giacomini KM, Savic RM. Goswami S, et al. Clin Pharmacol Ther. 2014 Sep;96(3):370-9. doi: 10.1038/clpt.2014.109. Epub 2014 May 22. Clin Pharmacol Ther. 2014. PMID: 24853734 Free PMC article.
Genetic and epigenetic regulation of the organic cation transporter 3, SLC22A3.
Chen L, Hong C, Chen EC, Yee SW, Xu L, Almof EU, Wen C, Fujii K, Johns SJ, Stryke D, Ferrin TE, Simko J, Chen X, Costello JF, Giacomini KM. Chen L, et al. Pharmacogenomics J. 2013 Apr;13(2):110-20. doi: 10.1038/tpj.2011.60. Epub 2012 Jan 10. Pharmacogenomics J. 2013. PMID: 22231567 Free PMC article.
The UCSF-FDA TransPortal: a public drug transporter database.
Morrissey KM, Wen CC, Johns SJ, Zhang L, Huang SM, Giacomini KM. Morrissey KM, et al. Among authors: wen cc. Clin Pharmacol Ther. 2012 Nov;92(5):545-6. doi: 10.1038/clpt.2012.44. Clin Pharmacol Ther. 2012. PMID: 23085876 Free PMC article.
138 results