Ralphe JC - Search Results

1

Neonatal mouse-derived engineered cardiac tissue: a novel model system for studying genetic heart disease.

de Lange WJ, Hegge LF, Grimes AC, Tong CW, Brost TM, Moss RL, Ralphe JC. de Lange WJ, et al. Among authors: ralphe jc. Circ Res. 2011 Jun 24;109(1):8-19. doi: 10.1161/CIRCRESAHA.111.242354. Epub 2011 May 12. Circ Res. 2011. PMID: 21566213 Free PMC article.

2

Ablation of cardiac myosin-binding protein-C accelerates contractile kinetics in engineered cardiac tissue.

de Lange WJ, Grimes AC, Hegge LF, Ralphe JC. de Lange WJ, et al. Among authors: ralphe jc. J Gen Physiol. 2013 Jan;141(1):73-84. doi: 10.1085/jgp.201210837. J Gen Physiol. 2013. PMID: 23277475 Free PMC article.

3

3D engineered cardiac tissue models of human heart disease: learning more from our mice.

Ralphe JC, de Lange WJ. Ralphe JC, et al. Trends Cardiovasc Med. 2013 Feb;23(2):27-32. doi: 10.1016/j.tcm.2012.08.007. Epub 2013 Jan 5. Trends Cardiovasc Med. 2013. PMID: 23295081 Free PMC article. Review.

4

E258K HCM-causing mutation in cardiac MyBP-C reduces contractile force and accelerates twitch kinetics by disrupting the cMyBP-C and myosin S2 interaction.

De Lange WJ, Grimes AC, Hegge LF, Spring AM, Brost TM, Ralphe JC. De Lange WJ, et al. Among authors: ralphe jc. J Gen Physiol. 2013 Sep;142(3):241-55. doi: 10.1085/jgp.201311018. J Gen Physiol. 2013. PMID: 23980194 Free PMC article.

5

Pompe disease results in a Golgi-based glycosylation deficit in human induced pluripotent stem cell-derived cardiomyocytes.

Raval KK, Tao R, White BE, De Lange WJ, Koonce CH, Yu J, Kishnani PS, Thomson JA, Mosher DF, Ralphe JC, Kamp TJ. Raval KK, et al. Among authors: ralphe jc. J Biol Chem. 2015 Jan 30;290(5):3121-36. doi: 10.1074/jbc.M114.628628. Epub 2014 Dec 8. J Biol Chem. 2015. PMID: 25488666 Free PMC article.

6

Cardiac MyBP-C regulates the rate and force of contraction in mammalian myocardium.

Moss RL, Fitzsimons DP, Ralphe JC. Moss RL, et al. Among authors: ralphe jc. Circ Res. 2015 Jan 2;116(1):183-92. doi: 10.1161/CIRCRESAHA.116.300561. Circ Res. 2015. PMID: 25552695 Free PMC article. Review.

7

Molecular Approaches in HFpEF: MicroRNAs and iPSC-Derived Cardiomyocytes.

Kriegel AJ, Gartz M, Afzal MZ, de Lange WJ, Ralphe JC, Strande JL. Kriegel AJ, et al. Among authors: ralphe jc. J Cardiovasc Transl Res. 2017 Jun;10(3):295-304. doi: 10.1007/s12265-016-9723-z. Epub 2016 Dec 28. J Cardiovasc Transl Res. 2017. PMID: 28032312 Free PMC article. Review.

8

Increased Postnatal Cardiac Hyperplasia Precedes Cardiomyocyte Hypertrophy in a Model of Hypertrophic Cardiomyopathy.

Farrell ET, Grimes AC, de Lange WJ, Armstrong AE, Ralphe JC. Farrell ET, et al. Among authors: ralphe jc. Front Physiol. 2017 Jun 14;8:414. doi: 10.3389/fphys.2017.00414. eCollection 2017. Front Physiol. 2017. PMID: 28659827 Free PMC article.

9

Linking metabolic and contractile dysfunction in aged cardiac myocytes.

Barton GP, de Lange WJ, Ralphe JC, Aiken J, Diffee G. Barton GP, et al. Among authors: ralphe jc. Physiol Rep. 2017 Nov;5(20):e13485. doi: 10.14814/phy2.13485. Epub 2017 Oct 29. Physiol Rep. 2017. PMID: 29084842 Free PMC article.

10

The HCM-linked W792R mutation in cardiac myosin-binding protein C reduces C6 FnIII domain stability.

Smelter DF, de Lange WJ, Cai W, Ge Y, Ralphe JC. Smelter DF, et al. Among authors: ralphe jc. Am J Physiol Heart Circ Physiol. 2018 Jun 1;314(6):H1179-H1191. doi: 10.1152/ajpheart.00686.2017. Epub 2018 Feb 16. Am J Physiol Heart Circ Physiol. 2018. PMID: 29451820 Free PMC article.

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