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Discovery of benzylisothioureas as potent divalent metal transporter 1 (DMT1) inhibitors.
Zhang Z, Kodumuru V, Sviridov S, Liu S, Chafeev M, Chowdhury S, Chakka N, Sun J, Gauthier SJ, Mattice M, Ratkay LG, Kwan R, Thompson J, Cutts AB, Fu J, Kamboj R, Goldberg YP, Cadieux JA. Zhang Z, et al. Among authors: liu s. Bioorg Med Chem Lett. 2012 Aug 1;22(15):5108-13. doi: 10.1016/j.bmcl.2012.05.129. Epub 2012 Jun 15. Bioorg Med Chem Lett. 2012. PMID: 22749870
Discovery of piperazin-1-ylpyridazine-based potent and selective stearoyl-CoA desaturase-1 inhibitors for the treatment of obesity and metabolic syndrome.
Zhang Z, Sun S, Kodumuru V, Hou D, Liu S, Chakka N, Sviridov S, Chowdhury S, McLaren DG, Ratkay LG, Khakh K, Cheng X, Gschwend HW, Kamboj R, Fu J, Winther MD. Zhang Z, et al. Among authors: liu s. J Med Chem. 2013 Jan 24;56(2):568-83. doi: 10.1021/jm301661h. Epub 2013 Jan 7. J Med Chem. 2013. PMID: 23245208
Discovery of Aryl Sulfonamides as Isoform-Selective Inhibitors of NaV1.7 with Efficacy in Rodent Pain Models.
Focken T, Liu S, Chahal N, Dauphinais M, Grimwood ME, Chowdhury S, Hemeon I, Bichler P, Bogucki D, Waldbrook M, Bankar G, Sojo LE, Young C, Lin S, Shuart N, Kwan R, Pang J, Chang JH, Safina BS, Sutherlin DP, Johnson JP Jr, Dehnhardt CM, Mansour TS, Oballa RM, Cohen CJ, Robinette CL. Focken T, et al. Among authors: liu s. ACS Med Chem Lett. 2016 Jan 19;7(3):277-82. doi: 10.1021/acsmedchemlett.5b00447. eCollection 2016 Mar 10. ACS Med Chem Lett. 2016. PMID: 26985315 Free PMC article.
77,469 results
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