Lebofsky M - Search Results

1

Apoptosis-inducing factor modulates mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Bajt ML, Ramachandran A, Yan HM, Lebofsky M, Farhood A, Lemasters JJ, Jaeschke H. Bajt ML, et al. Among authors: lebofsky m. Toxicol Sci. 2011 Aug;122(2):598-605. doi: 10.1093/toxsci/kfr116. Epub 2011 May 13. Toxicol Sci. 2011. PMID: 21572097 Free PMC article.

2

2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin (HxCDD) alter body weight by decreasing insulin-like growth factor I (IGF-I) signaling.

Croutch CR, Lebofsky M, Schramm KW, Terranova PF, Rozman KK. Croutch CR, et al. Among authors: lebofsky m. Toxicol Sci. 2005 May;85(1):560-71. doi: 10.1093/toxsci/kfi106. Epub 2005 Feb 9. Toxicol Sci. 2005. PMID: 15703265

3

Oxidant stress-induced liver injury in vivo: role of apoptosis, oncotic necrosis, and c-Jun NH2-terminal kinase activation.

Hong JY, Lebofsky M, Farhood A, Jaeschke H. Hong JY, et al. Among authors: lebofsky m. Am J Physiol Gastrointest Liver Physiol. 2009 Mar;296(3):G572-81. doi: 10.1152/ajpgi.90435.2008. Epub 2009 Jan 8. Am J Physiol Gastrointest Liver Physiol. 2009. PMID: 19136381 Free PMC article.

4

The strength of the Fas ligand signal determines whether hepatocytes act as type 1 or type 2 cells in murine livers.

Schüngel S, Buitrago-Molina LE, Nalapareddy Pd, Lebofsky M, Manns MP, Jaeschke H, Gross A, Vogel A. Schüngel S, et al. Among authors: lebofsky m. Hepatology. 2009 Nov;50(5):1558-66. doi: 10.1002/hep.23176. Hepatology. 2009. PMID: 19711425 Free PMC article.

5

The role of osteopontin and tumor necrosis factor alpha receptor-1 in xenobiotic-induced cholangitis and biliary fibrosis in mice.

Fickert P, Thueringer A, Moustafa T, Silbert D, Gumhold J, Tsybrovskyy O, Lebofsky M, Jaeschke H, Denk H, Trauner M. Fickert P, et al. Among authors: lebofsky m. Lab Invest. 2010 Jun;90(6):844-52. doi: 10.1038/labinvest.2010.61. Epub 2010 Apr 5. Lab Invest. 2010. PMID: 20368698 Free PMC article.

6

Cyclophilin D deficiency protects against acetaminophen-induced oxidant stress and liver injury.

Ramachandran A, Lebofsky M, Baines CP, Lemasters JJ, Jaeschke H. Ramachandran A, et al. Among authors: lebofsky m. Free Radic Res. 2011 Feb;45(2):156-64. doi: 10.3109/10715762.2010.520319. Epub 2010 Oct 13. Free Radic Res. 2011. PMID: 20942566 Free PMC article.

7

The impact of partial manganese superoxide dismutase (SOD2)-deficiency on mitochondrial oxidant stress, DNA fragmentation and liver injury during acetaminophen hepatotoxicity.

Ramachandran A, Lebofsky M, Weinman SA, Jaeschke H. Ramachandran A, et al. Among authors: lebofsky m. Toxicol Appl Pharmacol. 2011 Mar 15;251(3):226-33. doi: 10.1016/j.taap.2011.01.004. Epub 2011 Jan 15. Toxicol Appl Pharmacol. 2011. PMID: 21241727 Free PMC article.

8

Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury.

Ni HM, Boggess N, McGill MR, Lebofsky M, Borude P, Apte U, Jaeschke H, Ding WX. Ni HM, et al. Among authors: lebofsky m. Toxicol Sci. 2012 Jun;127(2):438-50. doi: 10.1093/toxsci/kfs133. Epub 2012 Apr 5. Toxicol Sci. 2012. PMID: 22491424 Free PMC article.

9

Purinergic receptor antagonist A438079 protects against acetaminophen-induced liver injury by inhibiting p450 isoenzymes, not by inflammasome activation.

Xie Y, Williams CD, McGill MR, Lebofsky M, Ramachandran A, Jaeschke H. Xie Y, et al. Among authors: lebofsky m. Toxicol Sci. 2013 Jan;131(1):325-35. doi: 10.1093/toxsci/kfs283. Epub 2012 Sep 17. Toxicol Sci. 2013. PMID: 22986947 Free PMC article.

10

Plasma and liver acetaminophen-protein adduct levels in mice after acetaminophen treatment: dose-response, mechanisms, and clinical implications.

McGill MR, Lebofsky M, Norris HR, Slawson MH, Bajt ML, Xie Y, Williams CD, Wilkins DG, Rollins DE, Jaeschke H. McGill MR, et al. Among authors: lebofsky m. Toxicol Appl Pharmacol. 2013 Jun 15;269(3):240-9. doi: 10.1016/j.taap.2013.03.026. Epub 2013 Apr 6. Toxicol Appl Pharmacol. 2013. PMID: 23571099 Free PMC article.

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