Huang L - Search Results

1

Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay.

Bruno IG, Karam R, Huang L, Bhardwaj A, Lou CH, Shum EY, Song HW, Corbett MA, Gifford WD, Gecz J, Pfaff SL, Wilkinson MF. Bruno IG, et al. Among authors: huang l. Mol Cell. 2011 May 20;42(4):500-10. doi: 10.1016/j.molcel.2011.04.018. Mol Cell. 2011. PMID: 21596314 Free PMC article.

2

An alternative branch of the nonsense-mediated decay pathway.

Chan WK, Huang L, Gudikote JP, Chang YF, Imam JS, MacLean JA 2nd, Wilkinson MF. Chan WK, et al. Among authors: huang l. EMBO J. 2007 Apr 4;26(7):1820-30. doi: 10.1038/sj.emboj.7601628. Epub 2007 Mar 15. EMBO J. 2007. PMID: 17363904 Free PMC article.

3

A UPF3-mediated regulatory switch that maintains RNA surveillance.

Chan WK, Bhalla AD, Le Hir H, Nguyen LS, Huang L, Gécz J, Wilkinson MF. Chan WK, et al. Among authors: huang l. Nat Struct Mol Biol. 2009 Jul;16(7):747-53. doi: 10.1038/nsmb.1612. Epub 2009 Jun 7. Nat Struct Mol Biol. 2009. PMID: 19503078

4

RNA homeostasis governed by cell type-specific and branched feedback loops acting on NMD.

Huang L, Lou CH, Chan W, Shum EY, Shao A, Stone E, Karam R, Song HW, Wilkinson MF. Huang L, et al. Mol Cell. 2011 Sep 16;43(6):950-61. doi: 10.1016/j.molcel.2011.06.031. Mol Cell. 2011. PMID: 21925383 Free PMC article.

5

Posttranscriptional control of the stem cell and neurogenic programs by the nonsense-mediated RNA decay pathway.

Lou CH, Shao A, Shum EY, Espinoza JL, Huang L, Karam R, Wilkinson MF. Lou CH, et al. Among authors: huang l. Cell Rep. 2014 Feb 27;6(4):748-64. doi: 10.1016/j.celrep.2014.01.028. Epub 2014 Feb 13. Cell Rep. 2014. PMID: 24529710 Free PMC article.

6

The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay.

Shum EY, Jones SH, Shao A, Chousal JN, Krause MD, Chan WK, Lou CH, Espinoza JL, Song HW, Phan MH, Ramaiah M, Huang L, McCarrey JR, Peterson KJ, De Rooij DG, Cook-Andersen H, Wilkinson MF. Shum EY, et al. Among authors: huang l. Cell. 2016 Apr 7;165(2):382-95. doi: 10.1016/j.cell.2016.02.046. Epub 2016 Mar 31. Cell. 2016. PMID: 27040500 Free PMC article.

7

Regulation of nonsense-mediated mRNA decay.

Huang L, Wilkinson MF. Huang L, et al. Wiley Interdiscip Rev RNA. 2012 Nov-Dec;3(6):807-28. doi: 10.1002/wrna.1137. Epub 2012 Oct 1. Wiley Interdiscip Rev RNA. 2012. PMID: 23027648 Review.

8

The unfolded protein response is shaped by the NMD pathway.

Karam R, Lou CH, Kroeger H, Huang L, Lin JH, Wilkinson MF. Karam R, et al. Among authors: huang l. EMBO Rep. 2015 May;16(5):599-609. doi: 10.15252/embr.201439696. Epub 2015 Mar 25. EMBO Rep. 2015. PMID: 25807986 Free PMC article.

9

Nonsense-mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR.

Keenan MM, Huang L, Jordan NJ, Wong E, Cheng Y, Valley HC, Mahiou J, Liang F, Bihler H, Mense M, Guo S, Monia BP. Keenan MM, et al. Among authors: huang l. Am J Respir Cell Mol Biol. 2019 Sep;61(3):290-300. doi: 10.1165/rcmb.2018-0316OC. Am J Respir Cell Mol Biol. 2019. PMID: 30836009

10

Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations.

Huang L, Low A, Damle SS, Keenan MM, Kuntz S, Murray SF, Monia BP, Guo S. Huang L, et al. Genome Biol. 2018 Jan 15;19(1):4. doi: 10.1186/s13059-017-1386-9. Genome Biol. 2018. PMID: 29334995 Free PMC article.

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