Summers MK - Search Results

1

Deubiquitinase USP37 is activated by CDK2 to antagonize APC(CDH1) and promote S phase entry.

Huang X, Summers MK, Pham V, Lill JR, Liu J, Lee G, Kirkpatrick DS, Jackson PK, Fang G, Dixit VM. Huang X, et al. Among authors: summers mk. Mol Cell. 2011 May 20;42(4):511-23. doi: 10.1016/j.molcel.2011.03.027. Mol Cell. 2011. PMID: 21596315 Free article.

2

The unique N terminus of the UbcH10 E2 enzyme controls the threshold for APC activation and enhances checkpoint regulation of the APC.

Summers MK, Pan B, Mukhyala K, Jackson PK. Summers MK, et al. Mol Cell. 2008 Aug 22;31(4):544-556. doi: 10.1016/j.molcel.2008.07.014. Mol Cell. 2008. PMID: 18722180 Free PMC article.

3

Cyclin E overexpression impairs progression through mitosis by inhibiting APC(Cdh1).

Keck JM, Summers MK, Tedesco D, Ekholm-Reed S, Chuang LC, Jackson PK, Reed SI. Keck JM, et al. Among authors: summers mk. J Cell Biol. 2007 Jul 30;178(3):371-85. doi: 10.1083/jcb.200703202. J Cell Biol. 2007. PMID: 17664332 Free PMC article.

4

Biochemical analysis of the Anaphase Promoting Complex: activities of E2 enzymes and substrate competitive (pseudosubstrate) inhibitors.

Summers MK, Jackson PK. Summers MK, et al. Methods Mol Biol. 2009;545:313-30. doi: 10.1007/978-1-60327-993-2_20. Methods Mol Biol. 2009. PMID: 19475398

5

Emi2 at the crossroads: where CSF meets MPF.

Hansen DV, Pomerening JR, Summers MK, Miller JJ, Ferrell JE Jr, Jackson PK. Hansen DV, et al. Among authors: summers mk. Cell Cycle. 2007 Mar 15;6(6):732-8. doi: 10.4161/cc.6.6.3937. Epub 2007 Mar 14. Cell Cycle. 2007. PMID: 17361104

6

APC/C(Cdc20) targets E2F1 for degradation in prometaphase.

Peart MJ, Poyurovsky MV, Kass EM, Urist M, Verschuren EW, Summers MK, Jackson PK, Prives C. Peart MJ, et al. Among authors: summers mk. Cell Cycle. 2010 Oct 1;9(19):3956-64. doi: 10.4161/cc.9.19.13162. Epub 2010 Oct 26. Cell Cycle. 2010. PMID: 20948288 Free PMC article.

7

The STARD9/Kif16a kinesin associates with mitotic microtubules and regulates spindle pole assembly.

Torres JZ, Summers MK, Peterson D, Brauer MJ, Lee J, Senese S, Gholkar AA, Lo YC, Lei X, Jung K, Anderson DC, Davis DP, Belmont L, Jackson PK. Torres JZ, et al. Among authors: summers mk. Cell. 2011 Dec 9;147(6):1309-23. doi: 10.1016/j.cell.2011.11.020. Cell. 2011. PMID: 22153075 Free PMC article.

8

A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs.

Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR 3rd, Jackson PK. Tung JJ, et al. Among authors: summers mk. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4318-23. doi: 10.1073/pnas.0501108102. Epub 2005 Mar 7. Proc Natl Acad Sci U S A. 2005. PMID: 15753281 Free PMC article.

9

Emi1 stably binds and inhibits the anaphase-promoting complex/cyclosome as a pseudosubstrate inhibitor.

Miller JJ, Summers MK, Hansen DV, Nachury MV, Lehman NL, Loktev A, Jackson PK. Miller JJ, et al. Among authors: summers mk. Genes Dev. 2006 Sep 1;20(17):2410-20. doi: 10.1101/gad.1454006. Epub 2006 Aug 18. Genes Dev. 2006. PMID: 16921029 Free PMC article.

10

Chk1-mediated phosphorylation of Cdh1 promotes the SCF^βTRCP-dependent degradation of Cdh1 during S-phase and efficient cell-cycle progression.

Pal D, Torres AE, Stromberg BR, Messina AL, Dickson AS, De K, Willard B, Venere M, Summers MK. Pal D, et al. Among authors: summers mk. Cell Death Dis. 2020 Apr 28;11(4):298. doi: 10.1038/s41419-020-2493-1. Cell Death Dis. 2020. PMID: 32345958 Free PMC article.

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