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Identification and in vivo and in vitro characterization of long acting and melanocortin 4 receptor (MC4-R) selective α-melanocyte-stimulating hormone (α-MSH) analogues.
Conde-Frieboes K, Thøgersen H, Lau JF, Sensfuss U, Hansen TK, Christensen L, Spetzler J, Olsen HB, Nilsson C, Raun K, Dahl K, Hansen BS, Wulff BS. Conde-Frieboes K, et al. J Med Chem. 2012 Mar 8;55(5):1969-77. doi: 10.1021/jm201489a. Epub 2012 Feb 24. J Med Chem. 2012. PMID: 22335602
UCP1-independent glucose-lowering effect of leptin in type 1 diabetes: only in conditions of hypoleptinemia.
Zouhar P, Rakipovski G, Bokhari MH, Busby O, Paulsson JF, Conde-Frieboes KW, Fels JJ, Raun K, Andersen B, Cannon B, Nedergaard J. Zouhar P, et al. Among authors: conde frieboes kw. Am J Physiol Endocrinol Metab. 2020 Jan 1;318(1):E72-E86. doi: 10.1152/ajpendo.00253.2019. Epub 2019 Nov 19. Am J Physiol Endocrinol Metab. 2020. PMID: 31743040 Free PMC article.
In vitro prediction of in vivo pseudo-allergenic response via MRGPRX2.
John LM, Dalsgaard CM, Jeppesen CB, Conde-Frieboes KW, Baumann K, Knudsen NPH, Skov PS, Wulff BS. John LM, et al. Among authors: conde frieboes kw. J Immunotoxicol. 2021 Dec;18(1):30-36. doi: 10.1080/1547691X.2021.1877375. J Immunotoxicol. 2021. PMID: 33570451 Free article.
Rational Development of Stable PYY3-36 Peptide Y2 Receptor Agonists.
Poulsen C, Pedersen MØ, Wahlund PO, Sjölander A, Thomsen JK, Conde-Frieboes KW, Paulsson JF, Wulff BS, Østergaard S. Poulsen C, et al. Among authors: conde frieboes kw. Pharm Res. 2021 Aug;38(8):1369-1385. doi: 10.1007/s11095-021-03077-x. Epub 2021 Jul 16. Pharm Res. 2021. PMID: 34272643
Demonstration of a Common DPhe7 to DNal(2')7 Peptide Ligand Antagonist Switch for Melanocortin-3 and Melanocortin-4 Receptors Identifies the Systematic Mischaracterization of the Pharmacological Properties of Melanocortin Peptides.
Gimenez LE, Noblin TA, Williams SY, Mullick Bagchi S, Ji RL, Tao YX, Jeppesen CB, Conde-Frieboes KW, Sawyer TK, Grieco P, Cone RD. Gimenez LE, et al. Among authors: conde frieboes kw. J Med Chem. 2022 Apr 28;65(8):5990-6000. doi: 10.1021/acs.jmedchem.1c01295. Epub 2022 Apr 11. J Med Chem. 2022. PMID: 35404053 Free PMC article.
20 results