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The JAK2/STAT3 signaling pathway is required for growth of CD44⁺CD24⁻ stem cell-like breast cancer cells in human tumors.
Marotta LL, Almendro V, Marusyk A, Shipitsin M, Schemme J, Walker SR, Bloushtain-Qimron N, Kim JJ, Choudhury SA, Maruyama R, Wu Z, Gönen M, Mulvey LA, Bessarabova MO, Huh SJ, Silver SJ, Kim SY, Park SY, Lee HE, Anderson KS, Richardson AL, Nikolskaya T, Nikolsky Y, Liu XS, Root DE, Hahn WC, Frank DA, Polyak K. Marotta LL, et al. Among authors: hahn wc. J Clin Invest. 2011 Jul;121(7):2723-35. doi: 10.1172/JCI44745. J Clin Invest. 2011. PMID: 21633165 Free PMC article.
Oncogenic transformation by inhibitor-sensitive and -resistant EGFR mutants.
Greulich H, Chen TH, Feng W, Jänne PA, Alvarez JV, Zappaterra M, Bulmer SE, Frank DA, Hahn WC, Sellers WR, Meyerson M. Greulich H, et al. Among authors: hahn wc. PLoS Med. 2005 Nov;2(11):e313. doi: 10.1371/journal.pmed.0020313. Epub 2005 Oct 4. PLoS Med. 2005. PMID: 16187797 Free PMC article.
Roots and stems: stem cells in cancer.
Polyak K, Hahn WC. Polyak K, et al. Among authors: hahn wc. Nat Med. 2006 Mar;12(3):296-300. doi: 10.1038/nm1379. Nat Med. 2006. PMID: 16520777
A lentiviral RNAi library for human and mouse genes applied to an arrayed viral high-content screen.
Moffat J, Grueneberg DA, Yang X, Kim SY, Kloepfer AM, Hinkle G, Piqani B, Eisenhaure TM, Luo B, Grenier JK, Carpenter AE, Foo SY, Stewart SA, Stockwell BR, Hacohen N, Hahn WC, Lander ES, Sabatini DM, Root DE. Moffat J, et al. Among authors: hahn wc. Cell. 2006 Mar 24;124(6):1283-98. doi: 10.1016/j.cell.2006.01.040. Cell. 2006. PMID: 16564017 Free article.
Androgen-dependent regulation of Her-2/neu in prostate cancer cells.
Berger R, Lin DI, Nieto M, Sicinska E, Garraway LA, Adams H, Signoretti S, Hahn WC, Loda M. Berger R, et al. Among authors: hahn wc. Cancer Res. 2006 Jun 1;66(11):5723-8. doi: 10.1158/0008-5472.CAN-05-3928. Cancer Res. 2006. PMID: 16740710
Cancer genomics: integrating form and function.
Kim SY, Hahn WC. Kim SY, et al. Among authors: hahn wc. Carcinogenesis. 2007 Jul;28(7):1387-92. doi: 10.1093/carcin/bgm086. Epub 2007 Apr 13. Carcinogenesis. 2007. PMID: 17434922 Review.
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC. Boehm JS, et al. Among authors: hahn wc. Cell. 2007 Jun 15;129(6):1065-79. doi: 10.1016/j.cell.2007.03.052. Cell. 2007. PMID: 17574021 Free article.
382 results