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A mutation of the beta 2-adrenergic receptor impairs agonist activation of adenylyl cyclase without affecting high affinity agonist binding. Distinct molecular determinants of the receptor are involved in physical coupling to and functional activation of Gs.
Hausdorff WP, Hnatowich M, O'Dowd BF, Caron MG, Lefkowitz RJ. Hausdorff WP, et al. Among authors: hnatowich m. J Biol Chem. 1990 Jan 25;265(3):1388-93. J Biol Chem. 1990. PMID: 2153131 Free article.
The 5-HT1A receptor: an overview of recent advances.
el Mestikawy S, Fargin A, Raymond JR, Gozlan H, Hnatowich M. el Mestikawy S, et al. Among authors: hnatowich m. Neurochem Res. 1991 Jan;16(1):1-10. doi: 10.1007/BF00965820. Neurochem Res. 1991. PMID: 2052135 Review.
37 results