Saw CL - Search Results

1

Pharmacodynamics of dietary phytochemical indoles I3C and DIM: Induction of Nrf2-mediated phase II drug metabolizing and antioxidant genes and synergism with isothiocyanates.

Saw CL, Cintrón M, Wu TY, Guo Y, Huang Y, Jeong WS, Kong AN. Saw CL, et al. Biopharm Drug Dispos. 2011 Jul;32(5):289-300. doi: 10.1002/bdd.759. Epub 2011 Jun 8. Biopharm Drug Dispos. 2011. PMID: 21656528 Free PMC article.

2

Induction of NRF2-mediated gene expression by dietary phytochemical flavones apigenin and luteolin.

Paredes-Gonzalez X, Fuentes F, Jeffery S, Saw CL, Shu L, Su ZY, Kong AN. Paredes-Gonzalez X, et al. Among authors: saw cl. Biopharm Drug Dispos. 2015 Oct;36(7):440-51. doi: 10.1002/bdd.1956. Epub 2015 Jul 15. Biopharm Drug Dispos. 2015. PMID: 25904312

3

Pharmacokinetics and pharmacodynamics of phase II drug metabolizing/antioxidant enzymes gene response by anticancer agent sulforaphane in rat lymphocytes.

Wang H, Khor TO, Yang Q, Huang Y, Wu TY, Saw CL, Lin W, Androulakis IP, Kong AN. Wang H, et al. Among authors: saw cl. Mol Pharm. 2012 Oct 1;9(10):2819-27. doi: 10.1021/mp300130k. Epub 2012 Sep 11. Mol Pharm. 2012. PMID: 22931102 Free PMC article.

4

Epigenetic reactivation of Nrf2 in murine prostate cancer TRAMP C1 cells by natural phytochemicals Z-ligustilide and Radix angelica sinensis via promoter CpG demethylation.

Su ZY, Khor TO, Shu L, Lee JH, Saw CL, Wu TY, Huang Y, Suh N, Yang CS, Conney AH, Wu Q, Kong AN. Su ZY, et al. Among authors: saw cl. Chem Res Toxicol. 2013 Mar 18;26(3):477-85. doi: 10.1021/tx300524p. Epub 2013 Mar 8. Chem Res Toxicol. 2013. PMID: 23441843

5

Epigenetic modifications of Nrf2 by 3,3'-diindolylmethane in vitro in TRAMP C1 cell line and in vivo TRAMP prostate tumors.

Wu TY, Khor TO, Su ZY, Saw CL, Shu L, Cheung KL, Huang Y, Yu S, Kong AN. Wu TY, et al. Among authors: saw cl. AAPS J. 2013 Jul;15(3):864-74. doi: 10.1208/s12248-013-9493-3. Epub 2013 May 9. AAPS J. 2013. PMID: 23658110 Free PMC article.

6

Anti-cancer and potential chemopreventive actions of ginseng by activating Nrf2 (NFE2L2) anti-oxidative stress/anti-inflammatory pathways.

Saw CL, Wu Q, Kong AN. Saw CL, et al. Chin Med. 2010 Oct 27;5:37. doi: 10.1186/1749-8546-5-37. Chin Med. 2010. PMID: 20979613 Free PMC article.

7

In vivo pharmacodynamics of indole-3-carbinol in the inhibition of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: involvement of Nrf2 and cell cycle/apoptosis signaling pathways.

Wu TY, Saw CL, Khor TO, Pung D, Boyanapalli SS, Kong AN. Wu TY, et al. Among authors: saw cl. Mol Carcinog. 2012 Oct;51(10):761-70. doi: 10.1002/mc.20841. Epub 2011 Aug 11. Mol Carcinog. 2012. PMID: 21837756

8

Dietary tocopherols inhibit cell proliferation, regulate expression of ERα, PPARγ, and Nrf2, and decrease serum inflammatory markers during the development of mammary hyperplasia.

Smolarek AK, So JY, Thomas PE, Lee HJ, Paul S, Dombrowski A, Wang CX, Saw CL, Khor TO, Kong AN, Reuhl K, Lee MJ, Yang CS, Suh N. Smolarek AK, et al. Among authors: saw cl. Mol Carcinog. 2013 Jul;52(7):514-25. doi: 10.1002/mc.21886. Epub 2012 Mar 2. Mol Carcinog. 2013. PMID: 22389237 Free PMC article.

9

A γ-tocopherol-rich mixture of tocopherols maintains Nrf2 expression in prostate tumors of TRAMP mice via epigenetic inhibition of CpG methylation.

Huang Y, Khor TO, Shu L, Saw CL, Wu TY, Suh N, Yang CS, Kong AN. Huang Y, et al. Among authors: saw cl. J Nutr. 2012 May;142(5):818-23. doi: 10.3945/jn.111.153114. Epub 2012 Mar 28. J Nutr. 2012. PMID: 22457388 Free PMC article.

10

Regulation of NF-E2-related factor 2 signaling for cancer chemoprevention: antioxidant coupled with antiinflammatory.

Hu R, Saw CL, Yu R, Kong AN. Hu R, et al. Among authors: saw cl. Antioxid Redox Signal. 2010 Dec 1;13(11):1679-98. doi: 10.1089/ars.2010.3276. Epub 2010 Aug 17. Antioxid Redox Signal. 2010. PMID: 20486765 Free PMC article. Review.

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