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SH3BP1, an exocyst-associated RhoGAP, inactivates Rac1 at the front to drive cell motility.
Mol Cell. 2011 Jun 10;42(5):650-61. doi: 10.1016/j.molcel.2011.03.032.
Mol Cell. 2011.
PMID: 21658605
Free PMC article.
Direct interaction between exocyst and Wave complexes promotes cell protrusions and motility.
Biondini M, Sadou-Dubourgnoux A, Paul-Gilloteaux P, Zago G, Arslanhan MD, Waharte F, Formstecher E, Hertzog M, Yu J, Guerois R, Gautreau A, Scita G, Camonis J, Parrini MC.
Biondini M, et al. Among authors: sadou dubourgnoux a.
J Cell Sci. 2016 Oct 15;129(20):3756-3769. doi: 10.1242/jcs.187336. Epub 2016 Sep 2.
J Cell Sci. 2016.
PMID: 27591259
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MAT2A inhibitor AG-270/S095033 in patients with advanced malignancies: a phase I trial.
Gounder M, Johnson M, Heist RS, Shapiro GI, Postel-Vinay S, Wilson FH, Garralda E, Wulf G, Almon C, Nabhan S, Aguado-Fraile E, He P, Romagnoli M, Hossain M, Narayanaswamy R, Sadou-Dubourgnoux A, Cooper M, Askoxylakis V, Burris HA, Tabernero J.
Gounder M, et al. Among authors: sadou dubourgnoux a.
Nat Commun. 2025 Jan 6;16(1):423. doi: 10.1038/s41467-024-55316-5.
Nat Commun. 2025.
PMID: 39762248
Free PMC article.
Clinical Trial.
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