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Page 1
BRAF mutations in hairy-cell leukemia.
Tiacci E, Trifonov V, Schiavoni G, Holmes A, Kern W, Martelli MP, Pucciarini A, Bigerna B, Pacini R, Wells VA, Sportoletti P, Pettirossi V, Mannucci R, Elliott O, Liso A, Ambrosetti A, Pulsoni A, Forconi F, Trentin L, Semenzato G, Inghirami G, Capponi M, Di Raimondo F, Patti C, Arcaini L, Musto P, Pileri S, Haferlach C, Schnittger S, Pizzolo G, Foà R, Farinelli L, Haferlach T, Pasqualucci L, Rabadan R, Falini B. Tiacci E, et al. Among authors: mannucci r. N Engl J Med. 2011 Jun 16;364(24):2305-15. doi: 10.1056/NEJMoa1014209. Epub 2011 Jun 11. N Engl J Med. 2011. PMID: 21663470 Free PMC article.
BRAF inhibitors reverse the unique molecular signature and phenotype of hairy cell leukemia and exert potent antileukemic activity.
Pettirossi V, Santi A, Imperi E, Russo G, Pucciarini A, Bigerna B, Schiavoni G, Fortini E, Spanhol-Rosseto A, Sportoletti P, Mannucci R, Martelli MP, Klein-Hitpass L, Falini B, Tiacci E. Pettirossi V, et al. Among authors: mannucci r. Blood. 2015 Feb 19;125(8):1207-16. doi: 10.1182/blood-2014-10-603100. Epub 2014 Dec 5. Blood. 2015. PMID: 25480661 Free PMC article. Clinical Trial.
Mutated nucleophosmin detects clonal multilineage involvement in acute myeloid leukemia: Impact on WHO classification.
Pasqualucci L, Liso A, Martelli MP, Bolli N, Pacini R, Tabarrini A, Carini M, Bigerna B, Pucciarini A, Mannucci R, Nicoletti I, Tiacci E, Meloni G, Specchia G, Cantore N, Di Raimondo F, Pileri S, Mecucci C, Mandelli F, Martelli MF, Falini B. Pasqualucci L, et al. Among authors: mannucci r. Blood. 2006 Dec 15;108(13):4146-55. doi: 10.1182/blood-2006-06-026716. Epub 2006 Aug 22. Blood. 2006. PMID: 16926285 Free article.
Immunohistochemistry predicts nucleophosmin (NPM) mutations in acute myeloid leukemia.
Falini B, Martelli MP, Bolli N, Bonasso R, Ghia E, Pallotta MT, Diverio D, Nicoletti I, Pacini R, Tabarrini A, Galletti BV, Mannucci R, Roti G, Rosati R, Specchia G, Liso A, Tiacci E, Alcalay M, Luzi L, Volorio S, Bernard L, Guarini A, Amadori S, Mandelli F, Pane F, Lo-Coco F, Saglio G, Pelicci PG, Martelli MF, Mecucci C. Falini B, et al. Among authors: mannucci r. Blood. 2006 Sep 15;108(6):1999-2005. doi: 10.1182/blood-2006-03-007013. Epub 2006 May 23. Blood. 2006. PMID: 16720834 Free article.
Born to be exported: COOH-terminal nuclear export signals of different strength ensure cytoplasmic accumulation of nucleophosmin leukemic mutants.
Bolli N, Nicoletti I, De Marco MF, Bigerna B, Pucciarini A, Mannucci R, Martelli MP, Liso A, Mecucci C, Fabbiano F, Martelli MF, Henderson BR, Falini B. Bolli N, et al. Among authors: mannucci r. Cancer Res. 2007 Jul 1;67(13):6230-7. doi: 10.1158/0008-5472.CAN-07-0273. Cancer Res. 2007. PMID: 17616680 Free article.
Both carboxy-terminus NES motif and mutated tryptophan(s) are crucial for aberrant nuclear export of nucleophosmin leukemic mutants in NPMc+ AML.
Falini B, Bolli N, Shan J, Martelli MP, Liso A, Pucciarini A, Bigerna B, Pasqualucci L, Mannucci R, Rosati R, Gorello P, Diverio D, Roti G, Tiacci E, Cazzaniga G, Biondi A, Schnittger S, Haferlach T, Hiddemann W, Martelli MF, Gu W, Mecucci C, Nicoletti I. Falini B, et al. Among authors: mannucci r. Blood. 2006 Jun 1;107(11):4514-23. doi: 10.1182/blood-2005-11-4745. Epub 2006 Feb 2. Blood. 2006. PMID: 16455950 Free article.
IL-17-producing double-negative T cells are expanded in the peripheral blood, infiltrate the salivary gland and are partially resistant to corticosteroid therapy in patients with Sjögren's syndrome.
Alunno A, Bistoni O, Bartoloni Bocci E, Caterbi S, Bigerna B, Pucciarini A, Tabarrini A, Mannucci R, Beghelli D, Falini B, Gerli R. Alunno A, et al. Among authors: mannucci r. Reumatismo. 2013 Oct 31;65(4):192-8. doi: 10.4081/reumatismo.2013.192. Reumatismo. 2013. PMID: 24192564
47 results