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Nuclear receptors TR2 and TR4 recruit multiple epigenetic transcriptional corepressors that associate specifically with the embryonic β-type globin promoters in differentiated adult erythroid cells.
Cui S, Kolodziej KE, Obara N, Amaral-Psarris A, Demmers J, Shi L, Engel JD, Grosveld F, Strouboulis J, Tanabe O. Cui S, et al. Among authors: obara n. Mol Cell Biol. 2011 Aug;31(16):3298-311. doi: 10.1128/MCB.05310-11. Epub 2011 Jun 13. Mol Cell Biol. 2011. PMID: 21670149 Free PMC article.
Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.
Nakano Y, Imagawa S, Matsumoto K, Stockmann C, Obara N, Suzuki N, Doi T, Kodama T, Takahashi S, Nagasawa T, Yamamoto M. Nakano Y, et al. Among authors: obara n. Blood. 2004 Dec 15;104(13):4300-7. doi: 10.1182/blood-2004-04-1631. Epub 2004 Aug 24. Blood. 2004. PMID: 15328158 Free article.
245 results