Ross NC - Search Results

1

Novel opioid cyclic tetrapeptides: Trp isomers of CJ-15,208 exhibit distinct opioid receptor agonism and short-acting κ opioid receptor antagonism.

Ross NC, Reilley KJ, Murray TF, Aldrich JV, McLaughlin JP. Ross NC, et al. Br J Pharmacol. 2012 Feb;165(4b):1097-108. doi: 10.1111/j.1476-5381.2011.01544.x. Br J Pharmacol. 2012. PMID: 21671905 Free PMC article.

2

Alanine analogues of [D-Trp]CJ-15,208: novel opioid activity profiles and prevention of drug- and stress-induced reinstatement of cocaine-seeking behaviour.

Aldrich JV, Senadheera SN, Ross NC, Reilley KA, Ganno ML, Eans SE, Murray TF, McLaughlin JP. Aldrich JV, et al. Among authors: ross nc. Br J Pharmacol. 2014 Jul;171(13):3212-22. doi: 10.1111/bph.12664. Br J Pharmacol. 2014. PMID: 24588614 Free PMC article.

3

Synthesis of cyclic tetrapeptide CJ 15,208: a novel kappa opioid receptor antagonist.

Kulkarni SS, Ross NC, McLaughlin JP, Aldrich JV. Kulkarni SS, et al. Among authors: ross nc. Adv Exp Med Biol. 2009;611:269-70. doi: 10.1007/978-0-387-73657-0_121. Adv Exp Med Biol. 2009. PMID: 19400188 No abstract available.

4

Unexpected opioid activity profiles of analogues of the novel peptide kappa opioid receptor ligand CJ-15,208.

Aldrich JV, Kulkarni SS, Senadheera SN, Ross NC, Reilley KJ, Eans SO, Ganno ML, Murray TF, McLaughlin JP. Aldrich JV, et al. Among authors: ross nc. ChemMedChem. 2011 Sep 5;6(9):1739-45. doi: 10.1002/cmdc.201100113. Epub 2011 Jul 14. ChemMedChem. 2011. PMID: 21761566 Free PMC article.

5

Synthesis of CJ-15,208, a novel κ-opioid receptor antagonist.

Ross NC, Kulkarni SS, McLaughlin JP, Aldrich JV. Ross NC, et al. Tetrahedron Lett. 2010 Sep 20;51(38):5020-5023. doi: 10.1016/j.tetlet.2010.07.086. Tetrahedron Lett. 2010. PMID: 22865937 Free PMC article.

6

The macrocyclic peptide natural product CJ-15,208 is orally active and prevents reinstatement of extinguished cocaine-seeking behavior.

Aldrich JV, Senadheera SN, Ross NC, Ganno ML, Eans SO, McLaughlin JP. Aldrich JV, et al. Among authors: ross nc. J Nat Prod. 2013 Mar 22;76(3):433-8. doi: 10.1021/np300697k. Epub 2013 Jan 17. J Nat Prod. 2013. PMID: 23327691 Free PMC article.

7

Physical presence of nor-binaltorphimine in mouse brain over 21 days after a single administration corresponds to its long-lasting antagonistic effect on κ-opioid receptors.

Patkar KA, Wu J, Ganno ML, Singh HD, Ross NC, Rasakham K, Toll L, McLaughlin JP. Patkar KA, et al. Among authors: ross nc. J Pharmacol Exp Ther. 2013 Sep;346(3):545-54. doi: 10.1124/jpet.113.206086. Epub 2013 Jul 12. J Pharmacol Exp Ther. 2013. PMID: 23853171

8

Bias Factor and Therapeutic Window Correlate to Predict Safer Opioid Analgesics.

Schmid CL, Kennedy NM, Ross NC, Lovell KM, Yue Z, Morgenweck J, Cameron MD, Bannister TD, Bohn LM. Schmid CL, et al. Among authors: ross nc. Cell. 2017 Nov 16;171(5):1165-1175.e13. doi: 10.1016/j.cell.2017.10.035. Cell. 2017. PMID: 29149605 Free PMC article.

9

Optimization of a Series of Mu Opioid Receptor (MOR) Agonists with High G Protein Signaling Bias.

Kennedy NM, Schmid CL, Ross NC, Lovell KM, Yue Z, Chen YT, Cameron MD, Bohn LM, Bannister TD. Kennedy NM, et al. Among authors: ross nc. J Med Chem. 2018 Oct 11;61(19):8895-8907. doi: 10.1021/acs.jmedchem.8b01136. Epub 2018 Sep 24. J Med Chem. 2018. PMID: 30199635 Free PMC article.

10

Reactions of some cyclopentenones with selected cysteine derivatives and biological activities of the product thioethers.

Bickley JF, Ciucci A, Evans P, Roberts SM, Ross N, Santoro MG. Bickley JF, et al. Bioorg Med Chem. 2004 Jun 15;12(12):3221-7. doi: 10.1016/j.bmc.2004.03.061. Bioorg Med Chem. 2004. PMID: 15158790

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