Gounder M - Search Results

1

Rationally designed treatment for solid tumors with MAPK pathway activation: a phase I study of paclitaxel and bortezomib using an adaptive dose-finding approach.

Mehnert JM, Tan AR, Moss R, Poplin E, Stein MN, Sovak M, Levinson K, Lin H, Kane M, Gounder M, Lin Y, Shih WJ, White E, Rubin EH, Karantza V. Mehnert JM, et al. Among authors: gounder m. Mol Cancer Ther. 2011 Aug;10(8):1509-19. doi: 10.1158/1535-7163.MCT-10-0944. Epub 2011 Jun 16. Mol Cancer Ther. 2011. PMID: 21680752 Free PMC article. Clinical Trial.

2

Transcription-dependent degradation of topoisomerase I-DNA covalent complexes.

Desai SD, Zhang H, Rodriguez-Bauman A, Yang JM, Wu X, Gounder MK, Rubin EH, Liu LF. Desai SD, et al. Mol Cell Biol. 2003 Apr;23(7):2341-50. doi: 10.1128/MCB.23.7.2341-2350.2003. Mol Cell Biol. 2003. PMID: 12640119 Free PMC article.

3

Phase I evaluation of sequential topoisomerase targeting with irinotecan/cisplatin followed by etoposide in patients with advanced malignancy.

Licitra EJ, Vyas V, Nelson K, Musanti R, Beers S, Thomas C, Poplin E, Smith S, Lin Y, Schaaf LJ, Aisner J, Gounder M, Rajendra R, Saleem A, Toppmeyer D, Rubin EH. Licitra EJ, et al. Among authors: gounder m. Clin Cancer Res. 2003 May;9(5):1673-9. Clin Cancer Res. 2003. PMID: 12738720 Clinical Trial.

4

Differential effects of the breast cancer resistance protein on the cellular accumulation and cytotoxicity of 9-aminocamptothecin and 9-nitrocamptothecin.

Rajendra R, Gounder MK, Saleem A, Schellens JH, Ross DD, Bates SE, Sinko P, Rubin EH. Rajendra R, et al. Among authors: gounder mk. Cancer Res. 2003 Jun 15;63(12):3228-33. Cancer Res. 2003. PMID: 12810652

5

A phase I and pharmacologic study of the combination of marimastat and paclitaxel in patients with advanced malignancy.

Toppmeyer DL, Gounder M, Much J, Musanti R, Vyas V, Medina M, Orlando T, Pennick M, Lin Y, Shih W, Goodin S, Rubin E. Toppmeyer DL, et al. Among authors: gounder m. Med Sci Monit. 2003 Aug;9(8):PI99-104. Med Sci Monit. 2003. PMID: 12942041 Clinical Trial.

6

Development of a bioanalytical liquid chromatography method for quantitation of 9-nitrocamptothecin in human plasma.

Gounder MK, Sun SL, Sands H, Lin Y, Shih WJ, Gu Z, Charles-Williams S, Roychowdhury M, Rajendra R, Rubin EH. Gounder MK, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2004 Jan 5;799(1):63-72. doi: 10.1016/j.jchromb.2003.10.010. J Chromatogr B Analyt Technol Biomed Life Sci. 2004. PMID: 14659436

7

Phase I and pharmacokinetic study of imatinib mesylate (Gleevec) and gemcitabine in patients with refractory solid tumors.

Ali Y, Lin Y, Gharibo MM, Gounder MK, Stein MN, Lagattuta TF, Egorin MJ, Rubin EH, Poplin EA. Ali Y, et al. Among authors: gounder mk. Clin Cancer Res. 2007 Oct 1;13(19):5876-82. doi: 10.1158/1078-0432.CCR-07-0883. Clin Cancer Res. 2007. PMID: 17908982 Clinical Trial.

8

Effects of drug efflux proteins and topoisomerase I mutations on the camptothecin analogue gimatecan.

Gounder MK, Nazar AS, Saleem A, Pungaliya P, Kulkarni D, Versace R, Rubin EH. Gounder MK, et al. Invest New Drugs. 2008 Jun;26(3):205-13. doi: 10.1007/s10637-007-9093-0. Epub 2007 Oct 18. Invest New Drugs. 2008. PMID: 17943230

9

Sequential topoisomerase targeting and analysis of mechanisms of resistance to topotecan in patients with acute myelogenous leukemia.

Saraiya B, Gounder M, Dutta J, Saleem A, Collazo C, Zimmerman L, Nazar A, Gharibo M, Schaar D, Lin Y, Shih W, Aisner J, Strair RK, Rubin EH. Saraiya B, et al. Among authors: gounder m. Anticancer Drugs. 2008 Apr;19(4):411-20. doi: 10.1097/CAD.0b013e3282f5218b. Anticancer Drugs. 2008. PMID: 18454051 Clinical Trial.

10

Deficiency of the dual ubiquitin/SUMO ligase Topors results in genetic instability and an increased rate of malignancy in mice.

Marshall H, Bhaumik M, Aviv H, Moore D, Yao M, Dutta J, Rahim H, Gounder M, Ganesan S, Saleem A, Rubin E. Marshall H, et al. Among authors: gounder m. BMC Mol Biol. 2010 Apr 29;11:31. doi: 10.1186/1471-2199-11-31. BMC Mol Biol. 2010. PMID: 20429939 Free PMC article.

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