Millard CJ - Search Results

1

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

Zhang L, Fairall L, Goult BT, Calkin AC, Hong C, Millard CJ, Tontonoz P, Schwabe JW. Zhang L, et al. Among authors: millard cj. Genes Dev. 2011 Jun 15;25(12):1262-74. doi: 10.1101/gad.2056211. Genes Dev. 2011. PMID: 21685362 Free PMC article.

2

Class I HDACs share a common mechanism of regulation by inositol phosphates.

Millard CJ, Watson PJ, Celardo I, Gordiyenko Y, Cowley SM, Robinson CV, Fairall L, Schwabe JW. Millard CJ, et al. Mol Cell. 2013 Jul 11;51(1):57-67. doi: 10.1016/j.molcel.2013.05.020. Epub 2013 Jun 20. Mol Cell. 2013. PMID: 23791785 Free PMC article.

3

Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting.

Itoh T, Fairall L, Muskett FW, Milano CP, Watson PJ, Arnaudo N, Saleh A, Millard CJ, El-Mezgueldi M, Martino F, Schwabe JW. Itoh T, et al. Among authors: millard cj. Nucleic Acids Res. 2015 Feb 27;43(4):2033-44. doi: 10.1093/nar/gkv068. Epub 2015 Feb 4. Nucleic Acids Res. 2015. PMID: 25653165 Free PMC article.

4

An evolving understanding of nuclear receptor coregulator proteins.

Millard CJ, Watson PJ, Fairall L, Schwabe JW. Millard CJ, et al. J Mol Endocrinol. 2013 Nov 7;51(3):T23-36. doi: 10.1530/JME-13-0227. Print 2013 Dec. J Mol Endocrinol. 2013. PMID: 24203923 Free PMC article. Review.

5

Towards an understanding of the structure and function of MTA1.

Millard CJ, Fairall L, Schwabe JW. Millard CJ, et al. Cancer Metastasis Rev. 2014 Dec;33(4):857-67. doi: 10.1007/s10555-014-9513-5. Cancer Metastasis Rev. 2014. PMID: 25352341 Free PMC article. Review.

6

The structure of the core NuRD repression complex provides insights into its interaction with chromatin.

Millard CJ, Varma N, Saleh A, Morris K, Watson PJ, Bottrill AR, Fairall L, Smith CJ, Schwabe JW. Millard CJ, et al. Elife. 2016 Apr 21;5:e13941. doi: 10.7554/eLife.13941. Elife. 2016. PMID: 27098840 Free PMC article.

7

Targeting Class I Histone Deacetylases in a "Complex" Environment.

Millard CJ, Watson PJ, Fairall L, Schwabe JWR. Millard CJ, et al. Trends Pharmacol Sci. 2017 Apr;38(4):363-377. doi: 10.1016/j.tips.2016.12.006. Epub 2017 Jan 28. Trends Pharmacol Sci. 2017. PMID: 28139258 Review.

8

Recombinant protein expression for structural biology in HEK 293F suspension cells: a novel and accessible approach.

Portolano N, Watson PJ, Fairall L, Millard CJ, Milano CP, Song Y, Cowley SM, Schwabe JW. Portolano N, et al. Among authors: millard cj. J Vis Exp. 2014 Oct 16;(92):e51897. doi: 10.3791/51897. J Vis Exp. 2014. PMID: 25349981 Free PMC article.

9

The topology of chromatin-binding domains in the NuRD deacetylase complex.

Millard CJ, Fairall L, Ragan TJ, Savva CG, Schwabe JWR. Millard CJ, et al. Nucleic Acids Res. 2020 Dec 16;48(22):12972-12982. doi: 10.1093/nar/gkaa1121. Nucleic Acids Res. 2020. PMID: 33264408 Free PMC article.

10

The MiDAC histone deacetylase complex is essential for embryonic development and has a unique multivalent structure.

Turnbull RE, Fairall L, Saleh A, Kelsall E, Morris KL, Ragan TJ, Savva CG, Chandru A, Millard CJ, Makarova OV, Smith CJ, Roseman AM, Fry AM, Cowley SM, Schwabe JWR. Turnbull RE, et al. Among authors: millard cj. Nat Commun. 2020 Jun 26;11(1):3252. doi: 10.1038/s41467-020-17078-8. Nat Commun. 2020. PMID: 32591534 Free PMC article.

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