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Coordinate linkage of HIV evolution reveals regions of immunological vulnerability.
Dahirel V, Shekhar K, Pereyra F, Miura T, Artyomov M, Talsania S, Allen TM, Altfeld M, Carrington M, Irvine DJ, Walker BD, Chakraborty AK. Dahirel V, et al. Among authors: chakraborty ak. Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11530-5. doi: 10.1073/pnas.1105315108. Epub 2011 Jun 20. Proc Natl Acad Sci U S A. 2011. PMID: 21690407 Free PMC article.
Fast on-rates allow short dwell time ligands to activate T cells.
Govern CC, Paczosa MK, Chakraborty AK, Huseby ES. Govern CC, et al. Among authors: chakraborty ak. Proc Natl Acad Sci U S A. 2010 May 11;107(19):8724-9. doi: 10.1073/pnas.1000966107. Epub 2010 Apr 26. Proc Natl Acad Sci U S A. 2010. PMID: 20421471 Free PMC article.
CD4 and CD8 binding to MHC molecules primarily acts to enhance Lck delivery.
Artyomov MN, Lis M, Devadas S, Davis MM, Chakraborty AK. Artyomov MN, et al. Among authors: chakraborty ak. Proc Natl Acad Sci U S A. 2010 Sep 28;107(39):16916-21. doi: 10.1073/pnas.1010568107. Epub 2010 Sep 13. Proc Natl Acad Sci U S A. 2010. PMID: 20837541 Free PMC article.
Polyreactivity increases the apparent affinity of anti-HIV antibodies by heteroligation.
Mouquet H, Scheid JF, Zoller MJ, Krogsgaard M, Ott RG, Shukair S, Artyomov MN, Pietzsch J, Connors M, Pereyra F, Walker BD, Ho DD, Wilson PC, Seaman MS, Eisen HN, Chakraborty AK, Hope TJ, Ravetch JV, Wardemann H, Nussenzweig MC. Mouquet H, et al. Among authors: chakraborty ak. Nature. 2010 Sep 30;467(7315):591-5. doi: 10.1038/nature09385. Nature. 2010. PMID: 20882016 Free PMC article.
Evolving concepts of specificity in immune reactions.
Eisen HN, Chakraborty AK. Eisen HN, et al. Among authors: chakraborty ak. Proc Natl Acad Sci U S A. 2010 Dec 28;107(52):22373-80. doi: 10.1073/pnas.1012051108. Epub 2010 Dec 20. Proc Natl Acad Sci U S A. 2010. PMID: 21173256 Free PMC article.
398 results