Chao YS - Search Results

1

Inhibition of HIV-1 Tat-mediated transcription by a coumarin derivative, BPRHIV001, through the Akt pathway.

Lin PH, Ke YY, Su CT, Shiao HY, Hsieh HP, Chao YK, Lee CN, Kao CL, Chao YS, Chang SY. Lin PH, et al. Among authors: chao yk, chao ys. J Virol. 2011 Sep;85(17):9114-26. doi: 10.1128/JVI.00175-11. Epub 2011 Jun 22. J Virol. 2011. PMID: 21697490 Free PMC article.

2

Anti-influenza drug discovery: structure-activity relationship and mechanistic insight into novel angelicin derivatives.

Yeh JY, Coumar MS, Horng JT, Shiao HY, Kuo FM, Lee HL, Chen IC, Chang CW, Tang WF, Tseng SN, Chen CJ, Shih SR, Hsu JT, Liao CC, Chao YS, Hsieh HP. Yeh JY, et al. Among authors: chao ys. J Med Chem. 2010 Feb 25;53(4):1519-33. doi: 10.1021/jm901570x. J Med Chem. 2010. PMID: 20092255

3

Pyrazole compound BPR1P0034 with potent and selective anti-influenza virus activity.

Shih SR, Chu TY, Reddy GR, Tseng SN, Chen HL, Tang WF, Wu MS, Yeh JY, Chao YS, Hsu JT, Hsieh HP, Horng JT. Shih SR, et al. Among authors: chao ys. J Biomed Sci. 2010 Feb 23;17(1):13. doi: 10.1186/1423-0127-17-13. J Biomed Sci. 2010. PMID: 20178582 Free PMC article.

4

Anti-influenza drug discovery: identification of an orally bioavailable quinoline derivative through activity- and property-guided lead optimization.

Yeh JY, Coumar MS, Shiao HY, Lin TJ, Lee YC, Hung HC, Ko S, Kuo FM, Fang MY, Huang YL, Hsu JT, Yeh TK, Shih SR, Chao YS, Horng JT, Hsieh HP. Yeh JY, et al. Among authors: chao ys. ChemMedChem. 2012 Sep;7(9):1546-50. doi: 10.1002/cmdc.201200259. Epub 2012 Jul 23. ChemMedChem. 2012. PMID: 22821876

5

A cell-based high-throughput screen for epidermal growth factor receptor pathway inhibitors.

Lin WH, Song JS, Chang TY, Chang CY, Fu YN, Yeh CL, Wu SH, Huang YW, Fang MY, Lien TW, Hsieh HP, Chao YS, Huang SF, Tsai SF, Wang LM, Hsu JT, Chen YR. Lin WH, et al. Among authors: chao ys. Anal Biochem. 2008 Jun 1;377(1):89-94. doi: 10.1016/j.ab.2008.02.027. Epub 2008 Mar 4. Anal Biochem. 2008. PMID: 18358823

6

3D-QSAR-assisted drug design: identification of a potent quinazoline-based Aurora kinase inhibitor.

Ke YY, Shiao HY, Hsu YC, Chu CY, Wang WC, Lee YC, Lin WH, Chen CH, Hsu JT, Chang CW, Lin CW, Yeh TK, Chao YS, Coumar MS, Hsieh HP. Ke YY, et al. Among authors: chao ys. ChemMedChem. 2013 Jan;8(1):136-48. doi: 10.1002/cmdc.201200464. Epub 2012 Nov 22. ChemMedChem. 2013. PMID: 23172777

7

Aurora kinase inhibitors reveal mechanisms of HURP in nucleation of centrosomal and kinetochore microtubules.

Wu JM, Chen CT, Coumar MS, Lin WH, Chen ZJ, Hsu JT, Peng YH, Shiao HY, Lin WH, Chu CY, Wu JS, Lin CT, Chen CP, Hsueh CC, Chang KY, Kao LP, Huang CY, Chao YS, Wu SY, Hsieh HP, Chi YH. Wu JM, et al. Among authors: chao ys. Proc Natl Acad Sci U S A. 2013 May 7;110(19):E1779-87. doi: 10.1073/pnas.1220523110. Epub 2013 Apr 22. Proc Natl Acad Sci U S A. 2013. PMID: 23610398 Free PMC article.

8

Structure-based drug design of a novel family of PPARgamma partial agonists: virtual screening, X-ray crystallography, and in vitro/in vivo biological activities.

Lu IL, Huang CF, Peng YH, Lin YT, Hsieh HP, Chen CT, Lien TW, Lee HJ, Mahindroo N, Prakash E, Yueh A, Chen HY, Goparaju CM, Chen X, Liao CC, Chao YS, Hsu JT, Wu SY. Lu IL, et al. Among authors: chao ys. J Med Chem. 2006 May 4;49(9):2703-12. doi: 10.1021/jm051129s. J Med Chem. 2006. PMID: 16640330

9

Structure-based drug design and structural biology study of novel nonpeptide inhibitors of severe acute respiratory syndrome coronavirus main protease.

Lu IL, Mahindroo N, Liang PH, Peng YH, Kuo CJ, Tsai KC, Hsieh HP, Chao YS, Wu SY. Lu IL, et al. Among authors: chao ys. J Med Chem. 2006 Aug 24;49(17):5154-61. doi: 10.1021/jm060207o. J Med Chem. 2006. PMID: 16913704

10

Fast-forwarding hit to lead: aurora and epidermal growth factor receptor kinase inhibitor lead identification.

Coumar MS, Chu CY, Lin CW, Shiao HY, Ho YL, Reddy R, Lin WH, Chen CH, Peng YH, Leou JS, Lien TW, Huang CT, Fang MY, Wu SH, Wu JS, Chittimalla SK, Song JS, Hsu JT, Wu SY, Liao CC, Chao YS, Hsieh HP. Coumar MS, et al. Among authors: chao ys. J Med Chem. 2010 Jul 8;53(13):4980-8. doi: 10.1021/jm1000198. J Med Chem. 2010. PMID: 20550212

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