Fennell DA - Search Results

1

The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance.

Barbone D, Ryan JA, Kolhatkar N, Chacko AD, Jablons DM, Sugarbaker DJ, Bueno R, Letai AG, Coussens LM, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: fennell da. Cell Death Dis. 2011 Jun 23;2(6):e174. doi: 10.1038/cddis.2011.58. Cell Death Dis. 2011. PMID: 21697949 Free PMC article.

2

Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression.

Barbone D, Cheung P, Battula S, Busacca S, Gray SG, Longley DB, Bueno R, Sugarbaker DJ, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: fennell da. PLoS One. 2012;7(12):e52753. doi: 10.1371/journal.pone.0052753. Epub 2012 Dec 26. PLoS One. 2012. PMID: 23300762 Free PMC article.

3

Bcl-2 family proteins contribute to apoptotic resistance in lung cancer multicellular spheroids.

Yang TM, Barbone D, Fennell DA, Broaddus VC. Yang TM, et al. Among authors: fennell da. Am J Respir Cell Mol Biol. 2009 Jul;41(1):14-23. doi: 10.1165/rcmb.2008-0320OC. Epub 2008 Dec 18. Am J Respir Cell Mol Biol. 2009. PMID: 19097992 Free PMC article.

4

Analysis of Gene Expression in 3D Spheroids Highlights a Survival Role for ASS1 in Mesothelioma.

Barbone D, Van Dam L, Follo C, Jithesh PV, Zhang SD, Richards WG, Bueno R, Fennell DA, Broaddus VC. Barbone D, et al. Among authors: fennell da. PLoS One. 2016 Mar 16;11(3):e0150044. doi: 10.1371/journal.pone.0150044. eCollection 2016. PLoS One. 2016. PMID: 26982031 Free PMC article.

5

BAK and NOXA are critical determinants of mitochondrial apoptosis induced by bortezomib in mesothelioma.

Busacca S, Chacko AD, Klabatsa A, Arthur K, Sheaff M, Barbone D, Mutti L, Gunasekharan VK, Gorski JJ, El-Tanani M, Broaddus VC, Gaudino G, Fennell DA. Busacca S, et al. Among authors: fennell da. PLoS One. 2013 Jun 7;8(6):e65489. doi: 10.1371/journal.pone.0065489. Print 2013. PLoS One. 2013. PMID: 23762382 Free PMC article.

6

Exploiting BH3 only protein function for effective cancer therapy.

Fennell DA, Chacko A. Fennell DA, et al. Front Biosci. 2008 May 1;13:6682-92. doi: 10.2741/3181. Front Biosci. 2008. PMID: 18508687 Review.

7

BCL-2 family regulation by the 20S proteasome inhibitor bortezomib.

Fennell DA, Chacko A, Mutti L. Fennell DA, et al. Oncogene. 2008 Feb 21;27(9):1189-97. doi: 10.1038/sj.onc.1210744. Epub 2007 Sep 10. Oncogene. 2008. PMID: 17828309 Review.

8

Acquired differential regulation of caspase-8 in cisplatin-resistant non-small-cell lung cancer.

Paul I, Chacko AD, Stasik I, Busacca S, Crawford N, McCoy F, McTavish N, Wilson B, Barr M, O'Byrne KJ, Longley DB, Fennell DA. Paul I, et al. Among authors: fennell da. Cell Death Dis. 2012 Dec 20;3(12):e449. doi: 10.1038/cddis.2012.186. Cell Death Dis. 2012. PMID: 23254292 Free PMC article.

9

Platinum resistant cancer cells conserve sensitivity to BH3 domains and obatoclax induced mitochondrial apoptosis.

Crawford N, Chacko AD, Savage KI, McCoy F, Redmond K, Longley DB, Fennell DA. Crawford N, et al. Among authors: fennell da. Apoptosis. 2011 Mar;16(3):311-20. doi: 10.1007/s10495-010-0561-1. Apoptosis. 2011. PMID: 21107700

10

Vorinostat/SAHA-induced apoptosis in malignant mesothelioma is FLIP/caspase 8-dependent and HR23B-independent.

Hurwitz JL, Stasik I, Kerr EM, Holohan C, Redmond KM, McLaughlin KM, Busacca S, Barbone D, Broaddus VC, Gray SG, O'Byrne KJ, Johnston PG, Fennell DA, Longley DB. Hurwitz JL, et al. Among authors: fennell da. Eur J Cancer. 2012 May;48(7):1096-107. doi: 10.1016/j.ejca.2011.11.009. Epub 2011 Dec 10. Eur J Cancer. 2012. PMID: 22154545

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